Lethal Capecitabine Toxicity in Patients With Complete Dihydropyrimidine Dehydrogenase Deficiency Due to Ultra-Rare DPYD Variants

被引：3
|
作者：
van Kuilenburg, Andre B. P. [1 ]
Pleunis-van Empel, Marjolein C. H. [2 ]
Brouwer, Rick B. [3 ]
Sijben, Angelique E. J. [4 ]
Knapen, Daan G. [5 ]
Munnink, Thijs H. Oude [6 ]
van Zanden, Jelmer J. [7 ]
Janssens-Puister, Jenny [8 ]
Dobritzsch, Doreen [9 ]
Meinsma, Rutger [1 ]
Meijer-Jansen, Judith [1 ]
van Dooren, Silvy J. M. [1 ]
Vijzelaar, Raymon [10 ]
Pop, Ana [1 ]
Salomons, Gajja S. [1 ]
Maring, Jan Gerard [11 ,12 ]
Niezen-Koning, Klary E. [8 ]
机构：
[1] Univ Amsterdam, Amsterdam Univ Med Ctr, Canc Ctr Amsterdam, Amsterdam Gastroenterol Endocrinol Metab,Lab Genet, Amsterdam, Netherlands
[2] Med Spectrum Twente, Dept Oncol, Enschede, Netherlands
[3] Med Spectrum Twente, Dept Clin Chem & Lab Med, Medlon BV, Enschede, Netherlands
[4] Med Spectrum Twente, Dept Neurol, Enschede, Netherlands
[5] Univ Groningen, Univ Med Ctr Groningen, Dept Med Oncol, Groningen, Netherlands
[6] Univ Groningen, Univ Med Ctr Groningen, Amsterdam, Netherlands
[7] Martini Hosp Groningen, Certe Dept Clin Chem, Groningen, Netherlands
[8] Univ Groningen, Univ Med Ctr Groningen, Dept Lab Med, Groningen, Netherlands
[9] Uppsala Univ, Biomed Ctr, Dept Chem, Uppsala, Sweden
[10] MRC Holland bv, Amsterdam, Netherlands
[11] Isala, Dept Clin Pharm, Zwolle, Netherlands
[12] Isala, Dept Med Oncol, Zwolle, Netherlands
来源：
JCO PRECISION ONCOLOGY | 2024年 / 8卷
关键词：
FLUOROPYRIMIDINE THERAPY; GENOTYPE; MUTATION; DELETION; GENE;
D O I：
10.1200/PO.23.00599
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
[No abstract available]
引用
收藏
页数：7
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