Far From Checkmate: Gastrointestinal Neoplasia Risk in Patients With Pathogenic Variants in CHEK2

被引:1
|
作者
Sommovilla, Joshua [1 ,2 ]
Burke, Carol [1 ,2 ,3 ]
Liska, David [1 ,3 ]
机构
[1] Cleveland Clin, Digest Dis & Surg Inst, Dept Colorectal Surg, Cleveland, OH USA
[2] Cleveland Clin, Sanford R Weiss MD Ctr Hereditary Colorectal Neopl, Digest Dis Inst, Dept Colorectal Surg, Cleveland, OH USA
[3] Cleveland Clin, Digest Dis & Surg Inst, Dept Gastroenterol Hepatol & Nutr, Cleveland, OH USA
关键词
BREAST-CANCER; SUSCEPTIBILITY;
D O I
10.1097/DCR.0000000000003449
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
引用
收藏
页码:1225 / 1226
页数:2
相关论文
共 50 条
  • [31] Differences in Cancer Phenotypes Among Frequent CHEK2 Variants and Implications for Clinical Care-Checking CHEK2
    Bychkovsky, Brittany L.
    Agaoglu, Nihat B.
    Horton, Carolyn
    Zhou, Jing
    Yussuf, Amal
    Hemyari, Parichehr
    Richardson, Marcy E.
    Young, Colin
    LaDuca, Holly
    McGuinness, Deborah L.
    Scheib, Rochelle
    Garber, Judy E.
    Rana, Huma Q.
    JAMA ONCOLOGY, 2022, 8 (11) : 1598 - 1606
  • [32] Functional analysis of rare CHEK2 variants identified in breast cancer patients
    Fuentes Rios, Olivia
    Santamarina, Marta
    Vizoso, Angel
    Rodriguez, Belinda
    Crujeiras, Ana
    Vega Gliemmo, Ana Paula
    EUROPEAN JOURNAL OF HUMAN GENETICS, 2022, 30 (SUPPL 1) : 381 - 382
  • [33] Pathogenic Variants in CHEK2 Are Associated With an Adverse Prognosis in Symptomatic Early-Onset Breast Cancer
    Greville-Heygate, Stephanie L.
    Maishman, Tom
    Tapper, William J.
    Cutress, Ramsey, I
    Copson, Ellen
    Dunning, Alison M.
    Haywood, Linda
    Jones, Louise J.
    Eccles, Diana M.
    JCO PRECISION ONCOLOGY, 2020, 4 : 472 - 485
  • [34] Beyond CHEK2 in breast cancer: Search for additional moderately penetrant risk gene variants by analyzing the oligogenic disease course in CHEK2 mutation carriers
    Pohl, E.
    Borde, J.
    Hauke, J.
    Schmidt, S.
    Weber-Lassalle, K.
    Ernst, C.
    Niederacher, D.
    Arnold, N.
    Hellebrand, H.
    Meindl, A.
    Gehrig, A.
    Schmidt, G.
    Dutrannoy, V.
    Kast, K.
    Hahnen, E.
    Schmutzler, R.
    EUROPEAN JOURNAL OF HUMAN GENETICS, 2018, 26 : 535 - 536
  • [35] Association of Inherited Pathogenic Variants in Checkpoint Kinase 2 (CHEK2) With Susceptibility to Testicular Germ Cell Tumors
    AlDubayan, Saud H.
    Pyle, Louise C.
    Gamulin, Marija
    Kulis, Tomislav
    Moore, Nathanael D.
    Taylor-Weiner, Amaro
    Hamid, Anis A.
    Reardon, Brendan
    Wubbenhorst, Bradley
    Godse, Rama
    Vaughn, David J.
    Jacobs, Linda A.
    Meien, Stefanie
    Grgic, Mislav
    Kastelan, Zeljko
    Markt, Sarah C.
    Damrauer, Scott M.
    Rader, Daniel J.
    Kember, Rachel L.
    Loud, Jennifer T.
    Kanetsky, Peter A.
    Greene, Mark H.
    Sweeney, Christopher J.
    Kubisch, Christian
    Nathanson, Katherine L.
    Van Allen, Eliezer M.
    Stewart, Douglas R.
    Lessel, Davor
    Van Hout, Cristopher
    O'Dushlaine, Colm
    Li, Alexander
    McCarthy, Shane
    Marcketta, Anthony
    Ye, Bin
    Dostal, Tanya Teslovich
    Schurmann, Claudia
    Gurski, Lauren
    Sun, Dylan
    Liu, Daren
    Abecasis, Goncalo
    Marchini, Jonathan
    Reid, Jeffrey
    Ulloa, Ricardo
    Habegger, Lukas
    Penn, John
    Bai, Xiaodong
    Hahn, Young
    Staples, Jeffrey
    Maxwell, Evan
    Manoochehri, Kia
    JAMA ONCOLOGY, 2019, 5 (04) : 514 - 522
  • [36] “I wish that there was more info”: characterizing the uncertainty experienced by carriers of pathogenic ATM and/or CHEK2 variants
    Kathryn G. Reyes
    Cheyla Clark
    Meredith Gerhart
    Ainsley J. Newson
    Kelly E. Ormond
    Familial Cancer, 2022, 21 : 143 - 155
  • [37] A founder CHEK2 pathogenic variant in association with kidney cancer
    Brooks, Kassi
    Holman, Melissa
    Steding, Catherine
    Tucker, Megan
    CANCER GENETICS, 2022, 262 : 40 - 42
  • [38] Rare variants in BRCA2 and CHEK2 are associated with the risk of urinary tract cancers
    Yuqiu Ge
    Yunyan Wang
    Wei Shao
    Jing Jin
    Mulong Du
    Gaoxiang Ma
    Haiyan Chu
    Meilin Wang
    Zhengdong Zhang
    Scientific Reports, 6
  • [39] Beyond CHEK2 in breast cancer: Search for additional moderately penetrant risk gene variants by analyzing the oligogenic disease course in CHEK2 mutation carriers
    Pohl, E.
    Richters, L.
    Hauke, J.
    Ernst, C.
    Krober, S.
    Niederacher, D.
    Arnold, N.
    Ramser, J.
    Gross, E.
    Gehrig, A.
    Schmidt, G.
    Dutrannoy, V.
    Kast, K.
    Hahnen, E.
    Schmutzler, R.
    CANCER RESEARCH, 2017, 77
  • [40] Rare variants in BRCA2 and CHEK2 are associated with the risk of urinary tract cancers
    Ge, Yuqiu
    Wang, Yunyan
    Shao, Wei
    Jin, Jing
    Du, Mulong
    Ma, Gaoxiang
    Chu, Haiyan
    Wang, Meilin
    Zhang, Zhengdong
    SCIENTIFIC REPORTS, 2016, 6