Recent advances of bone tissue engineering: carbohydrate and ceramic materials, fundamental properties and advanced biofabrication strategies - a comprehensive review

被引：5

作者：

Khan, Muhammad Umar Aslam ^{[1
,2
]}

Aslam, Muhammad Azhar ^{[3
]}

Bin Abdullah, Mohd Faizal ^{[4
,5
]}

Abdal-Hay, Abdalla ^{[6
,7
]}

Gao, Wendong ^{[8
]}

Xiao, Yin ^{[8
]}

Stojanovic, Goran M. ^{[9
]}

机构：

[1] Qatar Univ, Dept Mech & Ind Engn, Doha 2713, Qatar

[2] Qatar Univ, Biomed Res Ctr, Doha 2713, Qatar

[3] Univ Engn & Technol, Dept Phys, Lahore 39161, Pakistan

[4] Univ Sains Malaysia, Sch Dent Sci, Oral & Maxillofacial Surg Unit, Hlth Campus, Kota Baharu 16150, Kelantan, Malaysia

[5] Univ Sains Malaysia, Hosp Univ Sains Malaysia, Oral & Maxillofacial Surg Unit, Hlth Campus, Kota Baharu 16150, Kelantan, Malaysia

[6] South Valley Univ, Fac Engn, Dept Engn Mat & Mech Design, Qena 83523, Egypt

[7] Univ Queensland, Sch Dent, 288 Herston Rd, Herston, QLD 4006, Australia

[8] Griffith Univ, Sch Med & Dent, Gold Coast Campus, Brisbane, Qld 4222, Australia

[9] Univ Novi Sad, Fac Tech Sci, TD Obradovica 6, Novi Sad 21000, Serbia

来源：

BIOMEDICAL MATERIALS | 2024年 / 19卷 / 05期

关键词：

bone tissue; carbohydrate polymers; biofabrication strategies; polysaccharide; tissue engineering; IN-VITRO EVALUATION; SCAFFOLDS; HYDROGELS; PECTIN; STEREOLITHOGRAPHY; MINERALIZATION; ANTIBACTERIAL; ARABINOXYLAN; FABRICATION; CAPACITY;

D O I：

10.1088/1748-605X/ad6b8a

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Bone is a dynamic tissue that can always regenerate itself through remodeling to maintain biofunctionality. This tissue performs several vital physiological functions. However, bone scaffolds are required for critical-size damages and fractures, and these can be addressed by bone tissue engineering. Bone tissue engineering (BTE) has the potential to develop scaffolds for repairing critical-size damaged bone. BTE is a multidisciplinary engineered scaffold with the desired properties for repairing damaged bone tissue. Herein, we have provided an overview of the common carbohydrate polymers, fundamental structural, physicochemical, and biological properties, and fabrication techniques for bone tissue engineering. We also discussed advanced biofabrication strategies and provided the limitations and prospects by highlighting significant issues in bone tissue engineering. There are several review articles available on bone tissue engineering. However, we have provided a state-of-the-art review article that discussed recent progress and trends within the last 3-5 years by emphasizing challenges and future perspectives.

引用

页数：32

共 215 条

[1] Role of offset and gradient architectures of 3-D melt electrowritten scaffold on differentiation and mineralization of osteoblasts [J].