Cognitive Impairment and Early-onset Cerebral Amyloid Angiopathy in a Middle-aged Man with a History of Childhood Traumatic Brain Injury

被引:1
作者
Suzuki, Kosuke [1 ]
Ataka, Takuya [1 ]
Kimura, Noriyuki [1 ]
Matsubara, Etsuro [1 ]
机构
[1] Oita Univ, Fac Med, Dept Neurol, Oita, Japan
关键词
cerebral amyloid angiopathy; lobar intracerebral hemorrhaging; cognitive impairment; Pittsburgh compound-B positron emission tomography; traumatic brain injury; DECADES; TRANSMISSION; HEMORRHAGE; ADULTS;
D O I
10.2169/internalmedicine.2681-23
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
We herein report the a 42-year-old man with early-onset cerebral amyloid angiopathy (CAA) and a history of traumatic brain injury and neurosurgery in childhood. Computed tomography revealed cognitive impairment and recurrent lobar intracerebral hemorrhaging. Magnetic resonance imaging indicated cerebral microbleeds, and Pittsburgh compound B positron emission tomography detected brain amyloid deposition, mainly in the region of trauma and occipital lobes. Interestingly, the patient had no genetic predispositions or relevant family history. This case suggests that a single traumatic brain injury or neurosurgery in childhood can cause early-onset CAA.
引用
收藏
页码:2547 / 2550
页数:4
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