Phototherapy for Psoriasis in the Age of Biologics

被引:0
作者
Sandoval, Aaron Gabriel W. [1 ]
Mahajan, Arjun [1 ]
Buzney, Elizabeth [2 ]
机构
[1] Harvard Med Sch, 25 Shattuck St, Boston, MA 02115 USA
[2] Brigham & Womens Hosp, Dept Dermatol, 221 Longwood Ave, Boston, MA 02115 USA
关键词
Psoriasis; Phototherapy; Biologics; Efficacy; PASI score; Treatment costs; Safety profile; UVB PHOTOTHERAPY; HEPATITIS-B; THERAPY; REACTIVATION;
D O I
10.1016/j.det.2024.02.002
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Phototherapy has significant utility as a therapy for psoriasis, particularly if matched to the right patient. It has acceptable efficacy and onset of action with some patients responding exceedingly well with a far more desirable systemic adverse effect profile. The ability to periodically discontinue therapy with potentially sustained periods of remission can help patients who desire to avoid long-term and continuous systemic therapies. For patients with localized psoriasis, excimer or small booth phototherapy can alleviate symptoms significantly while avoiding medication and systemic side effects. Additionally, phototherapy can be cost-effective in comparison to many biologics and small molecule therapies, despite requiring a time investment. Depending on insurance coverage, these costs benefits can accrue, particularly with the fixed up-front costs of home phototherapy. Given patients' risk profiles and treatment preferences, phototherapy for psoriasis continues to be an essential treatment option.
引用
收藏
页码:399 / 404
页数:6
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