Effectiveness of COVID-19 vaccination against school absenteeism in children and adolescents hospitalized with COVID-19

被引：1

作者：

Maltezou, Helena C. ^{[1
]}

Kontogianni, Stavroula ^{[2
]}

Michailidou, Elisavet ^{[3
,4
]}

Vergadi, Eleni ^{[5
]}

Giannouchos, Theodoros V. ^{[6
]}

Steletou, Evangelia ^{[7
]}

Sipsas, Nikolaos V. ^{[8
]}

Galanakis, Emmanouil ^{[5
]}

Syrogiannopoulos, George A. ^{[2
]}

Roilides, Emmanuel ^{[3
,4
]}

机构：

[1] Natl Publ Hlth Org, Directorate Res Studies & Documentat, Athens 15123, Greece

[2] Univ Thessaly, Dept Pediat, Larisa, Greece

[3] Aristotle Univ Thessaloniki, Sch Med, Dept Pediat 3, Thessaloniki, Greece

[4] Hippokrateion Hosp, Thessaloniki, Greece

[5] Univ Crete, Med Sch, Dept Pediat, Iraklion, Greece

[6] Univ Alabama Birmingham, Sch Publ Hlth, Dept Hlth Policy & Org, Birmingham, AL USA

[7] Univ Patras, Sch Med, Dept Pediat, Patras, Greece

[8] Natl & Kapodistrian Univ Athens, Gen Hosp Athens, Med Sch, Pathophysiol Dept,Laiko Gen Hosp Athens, Athens 11527, Greece

来源：

VACCINE | 2024年 / 42卷 / 12期

关键词：

COVID-19; Children; Adolescents; Vaccination; Vaccine effectiveness; School absenteeism; MESSENGER-RNA VACCINATION; AGED; 12-18; YEARS; UNITED-STATES;

D O I：

10.1016/j.vaccine.2024.03.075

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Background: COVID-19 vaccination has been recommended for children to protect them and to enable in-person educational and social activities. Methods: We estimated COVID-19 vaccination effectiveness (VE) against school absenteeism in children 5-17 years old hospitalized from September 1, 2021 through May 31, 2023. Full vaccination was defined as two vaccine doses. Results: We studied 231 children admitted to hospital with COVID-19, including 206 (89.2 %) unvaccinated/ partially vaccinated and 25 (10.8 %) fully vaccinated. Unvaccinated/partially vaccinated children were absent from school for longer periods compared to fully vaccinated children (median absence: 14 versus 10 days; pvalue = 0.05). Multivariable regression showed that full COVID-19 vaccination was associated with fewer days of absence compared to no/partial vaccination on average (adjusted relative risk: 0.77; 95 % CI: 0.61 to 0.98). COVID-19 VE was 50.7 % (95 % CI: -11.3 % to 78.2 %) for school absenteeism above the median duration of absenteeism. Conclusions: Full COVID-19 vaccination conferred protection against school absenteeism in hospitalized schoolaged children with COVID-19.

引用

页码：2941 / 2944

页数：4

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