Should We Still Use Therapeutic Plasma Exchange for Rapidly Progressive Glomerulonephritis in ANCA Associated Vasculitis?

被引：3

作者：

Kaplan, Andre A. ^{[1
]}

Szpirt, Wladimir M. ^{[2
]}

机构：

[1] Univ Connecticut, Ctr Hlth, Div Nephrol, Farmington, CT 06062 USA

[2] Univ Copenhagen, Rigshosp, Dept Nephrol, DK-2100 Copenhagen, Denmark

来源：

KIDNEY AND DIALYSIS | 2022年 / 2卷 / 03期

关键词：

therapeutic plasma exchange; PLEX; RPGN; ANCA; PEXIVAS; RANDOMIZED-TRIAL; IMMUNOSUPPRESSION; AUTOANTIBODIES; PLASMAPHERESIS; GBM;

D O I：

10.3390/kidneydial2030035

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

For over thirty-five years, available data suggested that therapeutic plasma exchange (TPE) was a useful treatment for patients with Rapidly Progressive Glomerulonephritis (RPGN) associated with ANCA Associated Vasculitis (AAV) and elevated creatinine levels. The publication of the PEXIVAS study has challenged this conclusion. This perspective will outline the history of this issue and present our assessment of the current status.

引用

页码：399 / 406

页数：8

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