Vulvar Cancer, Version 3.2024

被引：25

作者：

Abu-Rustum, Nadeem R. ^{[1
]}

Yashar, Catheryn M. ^{[2
]}

Arend, Rebecca ^{[3
]}

Barber, Emma ^{[4
]}

Bradley, Kristin ^{[5
]}

Brooks, Rebecca ^{[6
]}

Campos, Susana M. ^{[7
]}

Chino, Junzo ^{[8
]}

Chon, Hye Sook ^{[9
]}

Crispens, Marta Ann ^{[10
]}

Damast, Shari ^{[11
]}

Fisher, Christine M. ^{[12
]}

Frederick, Peter ^{[13
]}

Gaffney, David K. ^{[14
]}

Gaillard, Stephanie ^{[15
]}

Giuntoli II, Robert ^{[16
]}

Glaser, Scott ^{[17
]}

Holmes, Jordan ^{[18
]}

Howitt, Brooke E. ^{[19
]}

Kendra, Kari ^{[20
]}

Lea, Jayanthi ^{[21
]}

Lee, Nita ^{[22
]}

Mantia-Smaldone, Gina ^{[23
]}

Mariani, Andrea ^{[24
]}

Mutch, David ^{[25
,26
]}

Nagel, Christa ^{[20
]}

Nekhlyudov, Larissa ^{[7
,28
]}

Podoll, Mirna ^{[10
]}

Rodabaugh, Kerry ^{[27
]}

Salani, Ritu

Schorge, John ^{[29
]}

Siedel, Jean ^{[30
]}

Sisodia, Rachel ^{[31
]}

Soliman, Pamela ^{[32
]}

Ueda, Stefanie ^{[33
]}

Urban, Renata ^{[34
]}

Wethington, Stephanie L. ^{[15
]}

Wyse, Emily ^{[33
]}

Zanotti, Kristine ^{[35
,36
]}

McMillian, Nicole ^{[37
]}

Espinosa, Sara ^{[37
]}

机构：

[1] Mem Sloan Kettering Canc Ctr, New York, NY 10065 USA

[2] Univ Calif San Diego, Moores Canc Ctr, San Diego, CA 92093 USA

[3] UAB, ONeal Comprehens Canc Ctr, Birmingham, AL USA

[4] Northwestern Univ, Robert H Lurie Comprehens Canc Ctr, Evanston, IL USA

[5] Univ Wisconsin, Carbone Canc Ctr, Madison, WI USA

[6] Univ Calif Davis, Comprehens Canc Ctr, Davis, CA USA

[7] Dana Farber Brigham & Womens Canc Ctr, Boston, MA USA

[8] Duke Canc Inst, Durham, NC USA

[9] Mof fitt Canc Ctr, Tampa, FL USA

[10] Vanderbilt Ingram Canc Ctr, Nashville, TN USA

[11] Yale Canc Ctr, Smilow Canc Hosp, New Haven, CT USA

[12] Univ Colorado, Ctr Canc, Denver, CO 80202 USA

[13] Roswell Pk Comprehens Canc Ctr, Buffalo, NY USA

[14] Univ Utah, Huntsman Canc Inst, Salt Lake City, UT USA

[15] Johns Hopkins, Sidney Kimmel Comprehens Canc Ctr, Mcadoo, PA USA

[16] Univ Penn, Abramson Canc Ctr, Philadelphia, PA USA

[17] City Hope Natl Med Ctr, Natl Med Ctr, Monrovia, CA USA

[18] Indiana Univ, Melvin & Bren Simon Comprehens Canc Ctr, Indianapolis, IN USA

[19] Stanford Canc Inst, Stanford, CA 94305 USA

[20] Ohio State Univ, Solove Res Inst, James Canc Hosp, Columbus, OH USA

[21] UT Southwestern, Simmons Comprehens Canc Ctr, Dallas, TX USA

[22] UChicago, Med Comprehens Canc Ctr, Maywood, IL USA

[23] Fox Chase Canc Ctr, Philadelphia, PA USA

[24] Mayo Clin, Comprehens Canc Ctr, Phoenix, AZ USA

[25] Barnes Jewish Hosp, Siteman Canc Ctr, St Louis, MO USA

[26] Washington Univ, Sch Med, St Louis, MO USA

[27] Fred & Pamela Buffett Canc Ctr, Omaha, NE USA

[28] UCLA, Jonsson Comprehens Canc Ctr, Los Angeles, CA USA

[29] Univ Tennessee, St Jude Childrens Res Hosp, Hlth Sci Ctr, Knoxville, TN USA

[30] Univ Michigan, Rogel Canc Ctr, Ann Arbor, MI USA

[31] Mass Gen Canc Ctr, Boston, MA USA

[32] Univ Texas MD Anderson Canc Ctr, Houston, TX USA

[33] UCSF, Helen Diller Family Comprehens Canc Ctr, San Francisco, CA USA

[34] Fred Hutchinson Canc Ctr, Seattle, WA USA

[35] Univ Hosp Seidman Canc Ctr, Case Comprehens Canc Ctr, Cleveland, OH USA

[36] Cleveland Clin, Taussig Canc Inst, Cleveland, OH USA

[37] Natl Comprehens Canc Network, Philadelphia, PA USA

来源：

JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK | 2024年 / 22卷 / 02期

关键词：

SQUAMOUS-CELL CARCINOMA; LOCALLY ADVANCED-CARCINOMA; ADJUVANT RADIATION-THERAPY; POSITIVE SOLID TUMORS; PELVIC NODE RESECTION; PHASE-II TRIAL; PREOPERATIVE CHEMORADIATION; LONG-TERM; STAGE-I; DEFINITIVE CHEMORADIATION;

D O I：

10.6004/jnccn.2024.0013

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Vulvar cancer is annually diagnosed in an estimated 6,470 individuals and the vast majority are histologically squamous cell carcinomas. Vulvar cancer accounts for 5% to 8% of gynecologic malignancies. Known risk factors for vulvar cancer include increasing age, infection with human papillomavirus, cigarette smoking, in flammatory conditions affecting the vulva, and immunode ficiency. Most vulvar neoplasias are diagnosed at early stages. Rarer histologies exist and include melanoma, extramammary Paget 's disease, Bartholin gland adenocarcinoma, verrucous carcinoma, basal cell carcinoma, and sarcoma. This manuscript discusses recommendations outlined in the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for treatments, surveillance, systemic therapy options, and gynecologic survivorship.

引用

页码：117 / 135

页数：19

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