Current Developments in Michael Addition Reaction using Heterocycles as Convenient Michael Donors

被引:6
作者
Samanta, Barsha [1 ]
Panda, Bhabani Shankar [1 ]
Mohapatra, Seetaram [1 ]
Nayak, Sabita [1 ]
机构
[1] Ravenshaw Univ, Dept Chem, Organ Synth Lab, Cuttack 753003, Odisha, India
关键词
Heterocycles; Michael addition; Organocatalysis; Enzyme catalysis; Asymmetric catalysis; Transition metal catalysis; PROTEIN-SYNTHESIS; CONSTRUCTION; CHEMISTRY; DISCOVERY; UMPOLUNG; CASCADE;
D O I
10.1002/ajoc.202400193
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The Michael addition reaction, a cornerstone of contemporary organic synthesis, has witnessed a resurgence of interest owing to its ability to forge intricate carbon-carbon and carbon-heteroatom bonds. In the past few years, heterocyclic compounds have been rigorously used as Michael donors, owing to their architectural diversity and distinct reactivity with or without the presence of base/transition metals/organocatalysts. This review encapsulates the latest breakthroughs in chemistry involving Michael addition reaction using heterocyclic compounds as Michael donors. It delivers a comprehensive update on developments in Michael addition reaction triggered by potent heterocycles since 2017, highlighting novel and innovative methodologies, with strategic insights. This review explores the latest breakthroughs in chemistry involving the Michael addition reaction, employing heterocyclic compounds as donors. It offers a comprehensive update on developments in Michael addition reactions catalyzed by potent heterocycles since 2017. The review emphasizes novel and innovative methodologies, offering strategic insights into this evolving field. image
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页数:30
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