Comparison of alignment efficacy and arch dimensions changes with superelastic-, heat-activated-, and seven stranded coaxial nickel-titanium archwires during fixed orthodontic treatment - A double-blind randomized clinical trial

Objectives: The objectives of this study were to compare the alignment efficacy, changes in arch dimensions, and pain experience with three different nickel-titanium (NiTi) archwires. Material and Methods: Forty-five subjects were subjected to indirect bonding in the mandibular arch, and allocated to three groups using block randomization; Group 1 (0.014" Superelastic NiTi), Group 2 (0.014" 27 degrees Copper NiTi), and Group 3 (0.016" seven stranded coaxial NiTi archwire). The mandibular study models were retrieved periodically at 4-week intervals for 12 weeks, which were blinded to measure the change in Little's irregularity index (LII) and dental arch dimensions. Pain and discomfort were recorded with visual analog scale at five different time intervals, namely, immediately after bonding (0) and at 1-, 4-, 8-, and 12-h for initial 7 days. Repeated analysis of variance, Wilcoxon Signed-Rank test, post hoc Bonferroni test, and Friedman's test was applied for the comparison and was used for data analysis. Results: A significant reduction of LII score and increase inarch length, intercanine, interpremolar, and intermolar width (P P <= 0.001) were observed after 12 weeks among all groups. However, intergroup comparison showed significant mean changes only for intercanine width (Group 1 versus 3) and interpremolar width (Groups 1 and 3; Groups 2 and 3). All other variables were found to be insignificant at all-time intervals when compared among each group. The increase in pain score was maximum with Group 1and least with Group 3. Conclusion: All archwires were found to be effective in reducing the LII score. Nevertheless, Group 3 archwire could achieve reduction of LII to zero in 14% of subjects than Groups 1 and 2.