Potential of Natural Products in the Treatment of Glioma: Focus on Molecular Mechanisms

被引：0

作者：

Sheida, Amirhossein ^{[1
,2
]}

Farshadi, Marjan ^{[3
]}

Mirzaei, Amirhossein ^{[4
]}

Khalilabad, Shakiba Najjar ^{[4
]}

Zarepour, Fatemeh ^{[1
,2
]}

Taghavi, Seyed Pouya ^{[1
,2
]}

Khabr, Maryam Sadat Hosseini ^{[1
,2
]}

Ravaei, Fatemeh ^{[1
,2
]}

Rafiei, Sara ^{[5
,6
]}

Mosadeghi, Kimia ^{[1
,2
]}

Yazdani, Mohammad Sepehr ^{[1
,2
]}

Fakhraie, Ali ^{[1
,2
]}

Ghattan, Alireza ^{[1
,2
]}

Fard, Mohammad Masoud Zamani ^{[1
,2
]}

Shahyan, Maryam ^{[1
,2
]}

Rafiei, Moein ^{[1
,2
]}

Rahimian, Neda ^{[5
,6
]}

Zavareh, Sayyed Alireza Talaei ^{[7
]}

Mirzaei, Hamed ^{[8
]}

机构：

[1] Kashan Univ Med Sci, Student Res Comm, Kashan, Iran

[2] Kashan Univ Med Sci, Sch Med, Kashan, Iran

[3] Giamed Corp, Richmond Hill, ON, Canada

[4] Mashhad Univ Med Sci, Student Res Comm, Fac Med, Mashhad, Iran

[5] Iran Univ Med Sci IUMS, Inst Endocrinol & Metab, Endocrine Res Ctr, Tehran, Iran

[6] Iran Univ Med Sci, Firoozgar Hosp, Sch Med, Dept Internal Med, Tehran, Iran

[7] Kashan Univ Med Sci, Physiol Res Ctr, Inst Basic Sci, Kashan, Iran

[8] Kashan Univ Med Sci, Inst Basic Sci, Res Ctr Biochem & Nutr Metab Dis, Kashan, Iran

来源：

CELL BIOCHEMISTRY AND BIOPHYSICS | 2024年

关键词：

Glioma; Natural compounds; Molecular mechanisms; Bioactive compounds; PROTEIN-KINASE-C; HUMAN GLIOBLASTOMA CELLS; GROWTH-FACTOR RECEPTOR; FOCAL ADHESION KINASE; MEMBRANE-TYPE-1; MATRIX-METALLOPROTEINASE; EPITHELIAL-MESENCHYMAL TRANSITION; HEME-OXYGENASE EXPRESSION; LOW-DENSITY LIPOPROTEINS; IN-VITRO CYTOTOXICITY; B SIGNALING PATHWAY;

D O I：

10.1007/s12013-024-01447-x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Despite the waning of traditional treatments for glioma due to possible long-term issues, the healing possibilities of substances derived from nature have been reignited in the scientific community. These natural substances, commonly found in fruits and vegetables, are considered potential alternatives to pharmaceuticals, as they have been shown in prior research to impact pathways surrounding cancer progression, metastases, invasion, and resistance. This review will explore the supposed molecular mechanisms of different natural components, such as berberine, curcumin, coffee, resveratrol, epigallocatechin-3-gallate, quercetin, tanshinone, silymarin, coumarin, and lycopene, concerning glioma treatment. While the benefits of a balanced diet containing these compounds are widely recognized, there is considerable scope for investigating the efficacy of these natural products in treating glioma.

引用

页码：3157 / 3208

页数：52

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