Mechanisms underlying the development of type 1 diabetes in ART-treated people living with HIV: an enigmatic puzzle

被引：0
作者：
Zaongo, Silvere D. [1 ]
Zongo, Abel W. [2 ]
Chen, Yaokai [1 ]
机构：
[1] Chongqing Publ Hlth Med Ctr, Dept Infect Dis, Chongqing, Peoples R China
[2] Zhejiang Univ Technol, Coll Food Sci & Technol, Hangzhou, Peoples R China
来源：
FRONTIERS IN IMMUNOLOGY | 2024年 / 15卷
关键词：
HIV; antiretroviral therapy; ART; type; 1; diabetes; T1DM; mechanisms; CD4(+) T-CELLS; PLASMACYTOID DENDRITIC CELLS; PANCREATIC LYMPH-NODES; ANTIRETROVIRAL THERAPY; IMMUNE RECONSTITUTION; BETA-CELLS; B-CELLS; PERIPHERAL-BLOOD; INFECTION; ONSET;
D O I：
10.3389/fimmu.2024.1470308
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
The immunopathogenesis of HIV infection remains poorly understood. Despite the widespread use of effective modern antiretroviral therapy (ART), people living with HIV (PLWH) are known to develop several comorbidities, including type 1 diabetes (T1DM). However, the etiology and critical mechanisms accounting for the onset of T1DM in the preceding context remain unknown. This article proposes to address this topic in order to provide further understanding and future research directions.
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页数：14
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