Medical Optimization of Patients with Symptomatic Peripheral Arterial Disease

被引:0
作者
Abumoawad, Abdelrhman [1 ]
Okazaki, Ross A. [2 ,3 ]
Behrooz, Leili [4 ]
Eberhardt, Robert T. [2 ,3 ]
机构
[1] St Elizabeth Hosp, Dept Cardiovasc Med, Boston, MA USA
[2] Boston Univ, Chobanian & Avedisian Sch Med, Evans Dept Med, Sect Cardiovasc Med, Boston, MA USA
[3] Boston Univ, Whitaker Cardiovasc Inst, Chobanian & Avedisian Sch Med, Boston, MA USA
[4] Med Coll Wisconsin, Dept Cardiovasc Med, Milwaukee, WI USA
关键词
INTERMITTENT CLAUDICATION; ANTIPLATELET THERAPY; SKELETAL-MUSCLE; HIGH-RISK; COLLABORATIVE METAANALYSIS; CARDIOVASCULAR OUTCOMES; SECONDARY PREVENTION; SUPERVISED EXERCISE; WALKING PERFORMANCE; ASPIRIN;
D O I
10.1016/j.avsg.2024.01.027
中图分类号
R61 [外科手术学];
学科分类号
摘要
Peripheral artery disease (PAD) is a progressive disease associated with the occurrence of major adverse cardiovascular and limb events and elevated mortality rates. Symptoms of PAD, including claudication and chronic limb-threatening ischemia, impair functional capacity and lead to lower quality of life. The focus of current therapies is to minimize symptoms, improve quality of life, and reduce adverse cardiovascular and limb events. Among the medical therapies are antiplatelets, anticoagulants, antihypertensives, lipid lowering therapies, cilostazol and pentoxifylline, and novel blood sugar-lowering therapies, plus exercise therapy and smoking cessation. In this review, we discuss these evidence-based medical therapies that are available for patients with symptomatic PAD.
引用
收藏
页码:170 / 180
页数:11
相关论文
共 96 条
  • [1] 2017 ESC Guidelines on the Diagnosis and Treatment of Peripheral Arterial Diseases, in collaboration with the European Society for Vascular Surgery (ESVS)
    Aboyans, Victor
    Ricco, Jean-Baptiste
    Bartelink, Marie-Louise E. L.
    Bjorck, Martin
    Brodmann, Marianne
    Cohnert, Tina
    Collet, Jean-Philippe
    Czerny, Martin
    De Carlo, Marco
    Debus, Sebastian
    Espinola-Klein, Christine
    Kahan, Thomas
    Kownator, Serge
    Mazzolai, Lucia
    Naylor, A. Ross
    Roffi, Marco
    Roether, Joachim
    Sprynger, Muriel
    Tendera, Michal
    Tepe, Gunnar
    Venermo, Maarit
    Vlachopoulos, Charalambos
    Desormais, Ileana
    [J]. EUROPEAN HEART JOURNAL, 2018, 39 (09) : 763 - +
  • [2] Peripheral Artery Disease Leading to Major Amputation: Trends in Revascularization and Mortality Over 18 Years
    Abry, Lisa
    Weiss, Salome
    Makaloski, Vladimir
    Haynes, Alan G.
    Schmidli, Juerg
    Wyss, Thomas R.
    [J]. ANNALS OF VASCULAR SURGERY, 2022, 78 : 295 - 301
  • [3] The natural history of untreated severe or critical limb ischemia
    Abu Dabrh, Abd Moain
    Steffen, Mark W.
    Undavalli, Chaitanya
    Asi, Noor
    Wang, Zhen
    Elamin, Mohamed B.
    Conte, Michael S.
    Murad, Mohammad Hassan
    [J]. JOURNAL OF VASCULAR SURGERY, 2015, 62 (06) : 1642 - +
  • [4] Ethnic-specific prevalence of peripheral arterial disease in the United States
    Allison, Matthew A.
    Ho, Elena
    Denenberg, Julie O.
    Langer, Robert D.
    Newman, Anne B.
    Fabsitz, Richard R.
    Criqui, Michael H.
    [J]. AMERICAN JOURNAL OF PREVENTIVE MEDICINE, 2007, 32 (04) : 328 - 333
  • [5] Anand S, 2007, NEW ENGL J MED, V357, P217
  • [6] Rivaroxaban with or without aspirin in patients with stable peripheral or carotid artery disease: an international, randomised, double-blind, placebo-controlled trial
    Anand, Sonia S.
    Bosch, Jackie
    Eikelboom, John W.
    Connolly, Stuart J.
    Diaz, Rafael
    Widimsky, Peter
    Aboyans, Victor
    Alings, Marco
    Kakkar, Ajay K.
    Keltai, Katalin
    Maggioni, Aldo P.
    Lewis, Basil S.
    Stoerk, Stefan
    Zhu, Jun
    Lopez-Jaramillo, Patricio
    O'Donnell, Martin
    Commerford, Patrick J.
    Vinereanu, Dragos
    Pogosova, Nana
    Ryden, Lars
    Fox, Keith A. A.
    Bhatt, Deepak L.
    Misselwitz, Frank
    Varigos, John D.
    Vanassche, Thomas
    Avezum, Alvaro A.
    Chen, Edmond
    Branch, Kelley
    Leong, Darryl P.
    Bangdiwala, Shrikant I.
    Hart, Robert G.
    Yusuf, Salim
    [J]. LANCET, 2018, 391 (10117) : 219 - 229
  • [7] Antiplatelet Trialists' Collaboration, 1994, BMJ, V308, P81
  • [8] Association of Statin Dose With Amputation and Survival in Patients With Peripheral Artery Disease
    Arya, Shipra
    Khakharia, Anjali
    Binney, Zachary O.
    DeMartino, Randall R.
    Brewster, Luke P.
    Goodney, Philip P.
    Wilson, Peter W. F.
    [J]. CIRCULATION, 2018, 137 (14) : 1435 - 1446
  • [9] Baigent C, 2002, BMJ-BRIT MED J, V324, P71, DOI 10.1136/bmj.324.7329.71
  • [10] Epidemiology and Risk of Amputation in Patients With Diabetes Mellitus and Peripheral Artery Disease
    Barnes, J. Aaron
    Eid, Mark A.
    Creager, Mark A.
    Goodney, Philip P.
    [J]. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2020, 40 (08) : 1808 - 1817