Direct oral anticoagulants for treatment of venous thrombosis: illustrated review of appropriate use

被引：2

作者：

Khairani, Candrika D.

Bejjani, Antoine

Assi, Ali

Porio, Nicole

Talasaz, Azita H. ^{[1
,2
]}

Piazza, Gregory ^{[3
]}

Cushman, Mary ^{[4
]}

Bikdeli, Behnood ^{[3
,5
,6
,7
]}

机构：

[1] Harvard Med Sch, Brigham & Womens Hosp, Thrombosis Res Grp, Boston, MA USA

[2] Univ Tehran Med Sci, Fac Pharm, Dept Clin Pharm, Tehran, Iran

[3] Univ Tehran Med Sci, Tehran Heart Ctr, Tehran, Iran

[4] Harvard Med Sch, Brigham & Womens Hosp, Cardiovasc Med Div, Boston, MA USA

[5] Univ Vermont, Larner Coll Med, Dept Med, Burlington, VT USA

[6] Yale New Haven Hosp, Ctr Outcomes Res & Evaluat CORE, New Haven, CT USA

[7] Cardiovasc Res Fdn CRF, New York, NY USA

来源：

RESEARCH AND PRACTICE IN THROMBOSIS AND HAEMOSTASIS | 2024年 / 8卷 / 04期

关键词：

anticoagulants; direct oral anticoagulants; low-molecular-weight heparin; venous; DEEP-VEIN THROMBOSIS; EXTENDED TREATMENT; ASIAN PATIENTS; BODY-WEIGHT; THROMBOEMBOLISM; RIVAROXABAN; DABIGATRAN; APIXABAN; WARFARIN; EFFICACY;

D O I：

10.1016/j.rpth.2024.102424

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Direct oral anticoagulants (DOACs) have become the preferred option for treatment of venous thromboembolism due to their favorable profile compared with other agents such as vitamin K antagonists or low-molecular-weight heparin. However, findings from randomized controlled trials suggest efficacy and/or safety concerns with DOAC use in some clinical contexts. This illustrated review will summarize indications where DOACs have proven efficacy and safety, situations where they fall short, and situations where uncertainty remains compared with other treatments for venous thromboembolism.

引用

页数：12

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