The Prevention of Viral Infections: The Role of Intestinal Microbiota and Nutritional Factors

被引：0
作者：
Altomare, Annamaria [1 ,2 ]
Giovanetti, Marta [1 ,3 ,4 ]
Baldaro, Francesca [2 ]
Ciccozzi, Massimo [5 ]
Cicala, Michele [2 ,6 ]
Guarino, Michele Pier Luca [2 ,6 ]
机构：
[1] Univ Campus Biomed Roma, Dept Sci & Technol Sustainable Dev & One Hlth, I-00128 Rome, Italy
[2] Univ Campus Biomed Roma, Unit Gastroenterol, I-00128 Rome, Italy
[3] Fundacao Oswaldo Cruz, Inst Rene Rachou, BR-30190002 Belo Horizonte, Brazil
[4] Climate Amplified Dis & Epidem CLIMADE, BR-31110370 Bairro Floresta, Brazil
[5] Univ Campus Biomed Roma, Unit Med Stat & Mol Epidemiol, I-00128 Rome, Italy
[6] Fdn Policlin Campus Biomed Roma, Unit Gastroenterol & Digest Endoscopy, I-00128 Rome, Italy
来源：
NUTRIENTS | 2024年 / 16卷 / 15期
关键词：
viral infection; nutrition; microbiota; vitamins; probiotics; RESPIRATORY-TRACT INFECTIONS; LACTOBACILLUS-RHAMNOSUS GG; GUT MICROBIOTA; DOUBLE-BLIND; INFLUENZA VACCINATION; IMMUNE-RESPONSE; FATTY-ACIDS; INNATE; DIET; RECOGNITION;
D O I：
10.3390/nu16152445
中图分类号：
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号：
100403 ;
摘要：
Viral infections pose significant global challenges due to their rapid transmissibility. Therefore, preventing and treating these infections promptly is crucial to curbing their spread. This review focuses on the vital link between nutrition and viral infections, underscoring how dietary factors influence immune system modulation. Malnutrition, characterized by deficiencies in essential nutrients such as vitamins A, C, D, E, and zinc, can impair the immune system, thereby increasing vulnerability to viral infections and potentially leading to more severe health outcomes that complicate recovery. Additionally, emerging evidence highlights the role of commensal microbiota in immune regulation, which can affect hosts' susceptibility to infections. Specific dietary components, including bioactive compounds, vitamins, and probiotics, can beneficially modify gut microbiota, thus enhancing immune response and offering protection against viral infections. This review aims to elucidate the mechanisms by which dietary adjustments and gut microbiota impact the pathogenesis of viral infections, with a particular focus on strengthening the immune system.
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页数：15
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