Osteopenia;
Oxidative balance score;
ROS;
Bone mineral density;
BONE-MINERAL DENSITY;
NATIONAL-HEALTH;
STRESS;
FRACTURE;
CATENIN;
RISK;
D O I:
10.1007/s00586-024-08424-1
中图分类号:
R74 [神经病学与精神病学];
学科分类号:
摘要:
Purpose Current research suggests that oxidative stress may decrease bone mineral density (BMD) by disrupting bone metabolism balance. However, no study investigated the relationship between systemic oxidative stress status and adult BMD. This study aims to investigate whether oxidative balance score (OBS) is associated with BMD in adults under 40. Methods 3963 participants were selected from the National Health and Nutrition Survey (NHANES) from 2011 to 2018. OBS is scored based on 20 dietary and lifestyle factors. Weighted multiple logistic regression and restricted cubic splines were used to assess the correlation between OBS and osteopenia. Results After adjusting for confounding factors, the weighted logistic regression results showed that compared with the first tertile of OBS, the highest tertile had a 38% (OR: 0.62, 95% CI: 0.47-0.82) lower risk of osteopenia. The restrictive cubic spline curve indicates a significant nonlinear correlation between OBS and the risk of osteopenia. Conclusion The research findings emphasize the relationship between OBS and the risk of osteopenia in young adults. Adopting an antioxidant diet and lifestyle may help young adults to maintain bone mass.
机构:
Cent South Univ, Dept Cardiol, Xiangya Hosp 2, Changsha 410011, Peoples R ChinaCent South Univ, Dept Cardiol, Xiangya Hosp 2, Changsha 410011, Peoples R China
Wang, Kang
Jiang, Zhongbiao
论文数: 0引用数: 0
h-index: 0
机构:
Cent South Univ, Xiangya Hosp 2, Dept Radiol, Changsha 410011, Peoples R ChinaCent South Univ, Dept Cardiol, Xiangya Hosp 2, Changsha 410011, Peoples R China
Jiang, Zhongbiao
Zhou, Qin
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h-index: 0
机构:
Cent South Univ, Clin Res Ctr Breast Dis Hunan Prov, Dept Gen Surg, Xiangya Hosp 2, Changsha 410011, Peoples R ChinaCent South Univ, Dept Cardiol, Xiangya Hosp 2, Changsha 410011, Peoples R China
Zhou, Qin
Tang, Hanfen
论文数: 0引用数: 0
h-index: 0
机构:
Cent South Univ, Dept Nutr, Xiangya Hosp 2, Changsha 410011, Peoples R ChinaCent South Univ, Dept Cardiol, Xiangya Hosp 2, Changsha 410011, Peoples R China
机构:
Cent South Univ, Dept Cardiol, Xiangya Hosp 2, Changsha 410011, Peoples R ChinaCent South Univ, Dept Cardiol, Xiangya Hosp 2, Changsha 410011, Peoples R China
Wang, Kang
Jiang, Zhongbiao
论文数: 0引用数: 0
h-index: 0
机构:
Cent South Univ, Xiangya Hosp 2, Dept Radiol, Changsha 410011, Peoples R ChinaCent South Univ, Dept Cardiol, Xiangya Hosp 2, Changsha 410011, Peoples R China
Jiang, Zhongbiao
Zhou, Qin
论文数: 0引用数: 0
h-index: 0
机构:
Cent South Univ, Clin Res Ctr Breast Dis Hunan Prov, Dept Gen Surg, Xiangya Hosp 2, Changsha 410011, Peoples R ChinaCent South Univ, Dept Cardiol, Xiangya Hosp 2, Changsha 410011, Peoples R China
Zhou, Qin
Tang, Hanfen
论文数: 0引用数: 0
h-index: 0
机构:
Cent South Univ, Dept Nutr, Xiangya Hosp 2, Changsha 410011, Peoples R ChinaCent South Univ, Dept Cardiol, Xiangya Hosp 2, Changsha 410011, Peoples R China