Exploring Varied Treatment Strategies for Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)

被引:10
作者
Elshaer, Amani [1 ]
Chascsa, David M. H. [2 ,3 ]
Lizaola-Mayo, Blanca C. [2 ,3 ]
机构
[1] Mayo Clin, Dept Internal Med, Scottsdale, AZ 85054 USA
[2] Mayo Clin, Div Gastroenterol & Hepatol, Scottsdale, AZ 85054 USA
[3] Mayo Clin, Transplant Ctr, Dept Med, Scottsdale, AZ 85054 USA
来源
LIFE-BASEL | 2024年 / 14卷 / 07期
关键词
metabolic-associated steatotic liver disease; fibrosis; cirrhosis; obesity; weight loss; lifestyle modification; pharmacotherapy; bariatric surgery; LIFE-STYLE MODIFICATION; CLINICAL-PRACTICE UPDATE; GLUCAGON-LIKE PEPTIDE-1; CORONARY-HEART-DISEASE; FATTY LIVER; BARIATRIC SURGERY; INSULIN-RESISTANCE; WEIGHT-LOSS; NONALCOHOLIC STEATOHEPATITIS; AMERICAN ASSOCIATION;
D O I
10.3390/life14070844
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Metabolic dysfunction-associated steatotic liver disease (MASLD) represents a liver disorder characterized by steatosis with underlying metabolic risk factors. The prevalence of MASLD continues to rise, leading to increased patient risk of various complications. Recent research has been focused on new therapeutic strategies to reduce the incidence of MASLD and provide effective treatment plans to prevent further irreversible liver damage. The treatment approach is multifactorial, with a primary focus on weight loss and management of underlying comorbidities through lifestyle modifications, pharmacotherapy, or surgical options. Ongoing research is exploring new pharmacological therapies that could enhance the treatment of MASLD.
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页数:21
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