COVID-19 in Pediatric Populations

被引：3

作者：

Okuducu, Yanki K. ^{[1
,2
,3
]}

Mall, Marcus A. ^{[4
,5
,6
,7
,8
]}

Yonker, Lael M. ^{[1
,2
,3
]}

机构：

[1] Massachusetts Gen Hosp, Dept Pediat, Pulm Div, 175 Cambridge St,5 th floor, Boston, MA 02114 USA

[2] Massachusetts Gen Hosp, Mucosal Immunol & Biol Res Ctr, Boston, MA USA

[3] Harvard Med Sch, Boston, MA USA

[4] Charite Univ Med Berlin, Dept Pediat Resp Med Immunol & Crit Care Med, Augustenburger Pl 1, D-13353 Berlin, Germany

[5] Free Univ Berlin, D-13353 Berlin, Germany

[6] Humboldt Univ, D-13353 Berlin, Germany

[7] German Ctr Lung Res DZL, Berlin, Germany

[8] Charite Univ Med Berlin, Berlin Inst Hlth, Berlin, Germany

来源：

CLINICS IN CHEST MEDICINE | 2024年 / 45卷 / 03期

关键词：

COVID-19; Pediatric; Multisystem inflammatory in children; Long COVID; VACCINE; STATES;

D O I：

10.1016/j.ccm.2024.02.019

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

Since the outset of the pandemic in March 2020, remarkable strides have been made in understanding the viral pathogenicity of SARS-CoV-2, the pathomechanism of acute COVID-19 and postacute complications, and strategies to prevent severe disease. The eradication of SARSCoV-2 is unlikely, and we should expect the virus to continue to circulate through communities in fluctuations. Plus, viral variants will continue to occur, challenging our immunogenicity. Importantly, while most children gain immunity against SARS-CoV-2 through either natural infection or vaccination, millions of new, naive infants are born annually. Vaccination will remain a key tool for protecting against rare, yet severe disease, especially in younger children. Many questions remain, and future research is needed to optimally protect children from severe acute and post-acute complications of COVID-19.

引用

页码：675 / 684

页数：10

共 89 条

[1] Nasal ciliated cells are primary targets for SARS-CoV-2 replication in the early stage of COVID-19 [J].

Ahn, Ji Hoon ;

Kim, JungMo ;

Hong, Seon Pyo ;

Choi, Sung Yong ;

Yang, Myung Jin ;

Ju, Young Seok ;

Kim, Young Tae ;

Kim, Ho Min ;

Rahman, Md Tazikur ;

Chung, Man Ki ;

Hong, Sang Duk ;

Bae, Hosung ;

Lee, Chang-Seop ;

Koh, Gou Young .

JOURNAL OF CLINICAL INVESTIGATION, 2021, 131 (13)

[2] Evaluation of mRNA-1273 Vaccine in Children 6 Months to 5 Years of Age [J].

Anderson, E. J. ;

Creech, C. B. ;

Berthaud, V ;

Piramzadian, A. ;

Johnson, K. A. ;

Zervos, M. ;

Garner, F. ;

Griffin, C. ;

Palanpurwala, K. ;

Turner, M. ;

Gerber, J. ;

Bennett, R. L. ;

Ali, K. ;

Ampajwala, M. ;

Berman, G. ;

Nayak, J. ;

Chronis, C. ;

Rizzardi, B. ;

Muller, W. J. ;

Smith, C. A. ;

Fuchs, G. ;

Hsia, D. ;

Tomassini, J. E. ;

DeLucia, D. ;

Reuter, C. ;

Kuter, B. ;

Zhao, X. ;

Deng, W. ;

Zhou, H. ;

Schrempp, D. Ramirez ;

Hautzinger, K. ;

Girard, B. ;

Slobod, K. ;

McPhee, R. ;

Pajon, R. ;

Aunins, A. ;

Das, R. ;

Miller, J. M. ;

Ghamloush, S. Schnyder .

NEW ENGLAND JOURNAL OF MEDICINE, 2022, 387 (18) :1673-1687

[3]

[Anonymous], About us

[4]

[Anonymous], About us

[5] Sustained decrease in pediatric asthma emergency visits during the first year of the COVID-19 pandemic [J].

Arsenault, Samantha ;

Hoofman, Jacob ;

Poowuttikul, Pavadee ;

Secord, Elizabeth .

ALLERGY AND ASTHMA PROCEEDINGS, 2021, 42 (05) :400-402

[6] Compromised SARS-CoV-2-specific placental antibody transfer [J].

Atyeo, Caroline ;

Pullen, Krista M. ;

Bordt, Evan A. ;

Fischinger, Stephanie ;

Burke, John ;

Michell, Ashlin ;

Slein, Matthew D. ;

Loos, Carolin ;

Shook, Lydia L. ;

Boatin, Adeline A. ;

Yockey, Laura J. ;

Pepin, David ;

Meinsohn, Marie-Charlotte ;

Nguyen, Ngoc Minh Phuong ;

Chauvin, Maeva ;

Roberts, Drucilla ;

Goldfarb, Ilona T. ;

Matute, Juan D. ;

James, Kaitlyn E. ;

Yonker, Lael M. ;

Bebell, Lisa M. ;

Kaimal, Anjali J. ;

Gray, Kathryn J. ;

Lauffenburger, Douglas ;

Edlow, Andrea G. ;

Alter, Galit .

CELL, 2021, 184 (03) :628-+

[7] Maternal immune response and placental antibody transfer after COVID-19 vaccination across trimester and platforms [J].

Atyeo, Caroline G. ;

Shook, Lydia L. ;

Brigida, Sara ;

De Guzman, Rose M. ;

Demidkin, Stepan ;

Muir, Cordelia ;

Akinwunmi, Babatunde ;

Baez, Arantxa Medina ;

McSweeney, Erin ;

Burns, Madeleine ;

Nayak, Ruhi ;

Kumar, Maya K. ;

Patel, Chinmay D. ;

Fialkowski, Allison ;

Cvrk, Dana ;

Goldfarb, Ilona T. ;

Yonker, Lael M. ;

Fasano, Alessio ;

Balazs, Alejandro B. ;

Elovitz, Michal A. ;

Gray, Kathryn J. ;

Alter, Galit ;

Edlow, Andrea G. .

NATURE COMMUNICATIONS, 2022, 13 (01)

[8] SARS-CoV-2 mRNA vaccination elicits robust antibody responses in children [J].

Bartsch, Yannic C. ;

St Denis, Kerri J. ;

Kaplonek, Paulina ;

Kang, Jaewon ;

Lam, Evan C. ;

Burns, Madeleine D. ;

Farkas, Eva J. ;

Davis, Jameson P. ;

Boribong, Brittany P. ;

Edlow, Andrea G. ;

Fasano, Alessio ;

Shreffler, Wayne G. ;

Zavadska, Dace ;

Johnson, Marina ;

Goldblatt, David ;

Balazs, Alejandro B. ;

Yonker, Lael M. ;

Alter, Galit .

SCIENCE TRANSLATIONAL MEDICINE, 2022, 14 (672)

[9] BNT162b2 induces robust cross-variant SARS-CoV-2 immunity in children [J].

Bartsch, Yannic C. ;

Chen, Jessica W. W. ;

Kang, Jaewon ;

Burns, Madeleine D. ;

St Denis, Kerri J. ;

Sheehan, Maegan L. ;

Davis, Jameson P. ;

Edlow, Andrea G. ;

Balazs, Alejandro B. ;

Yonker, Lael M. ;

Alter, Galit .

NPJ VACCINES, 2022, 7 (01)

[10] Humoral signatures of protective and pathological SARS-CoV-2 infection in children [J].

Bartsch, Yannic C. ;

Wang, Chuangqi ;

Zohar, Tomer ;

Fischinger, Stephanie ;

Atyeo, Caroline ;

Burke, John S. ;

Kang, Jaewon ;

Edlow, Andrea G. ;

Fasano, Alessio ;

Baden, Lindsey R. ;

Nilles, Eric J. ;

Woolley, Ann E. ;

Karlson, Elizabeth W. ;

Hopke, Alex R. ;

Irimia, Daniel ;

Fischer, Eric S. ;

Ryan, Edward T. ;

Charles, Richelle C. ;

Julg, Boris D. ;

Lauffenburger, Douglas A. ;

Yonker, Lael M. ;

Alter, Galit .

NATURE MEDICINE, 2021, 27 (03) :454-+

← 1 2 3 4 5 6 7 8 9 →