Ballistic Gels in Experimental Fracture Setting

被引:1
作者
Biehl, Christoph [1 ,2 ]
Thiesse-Kraul, Ann-Cathrin [2 ]
Stoetzel, Sabine [2 ]
Alzubi, Salsabel [2 ]
Biehl, Lotta [3 ]
Muelke, Matthias [1 ,2 ]
Heiss, Christian [1 ,2 ]
El Khassawna, Thaqif [2 ,4 ]
机构
[1] Justus Liebig Univ Giessen, Fac Med, Dept Trauma Hand & Reconstruct Surg, D-35392 Giessen, Germany
[2] Justus Liebig Univ Giessen, Fac Med, Expt Trauma Surg, D-35392 Giessen, Germany
[3] Heidelberg Univ, Med Fac Heidelberg, D-69117 Heidelberg, Germany
[4] Univ Jordan, Sch Pharm, Amman 11942, Jordan
基金
奥地利科学基金会;
关键词
ballistic gel; fracture model; pressure loads; biomechanical testing; FRAGMENT SIMULATING PROJECTILES; PENETRATION; MODEL; GELATIN; TISSUE; IMPACT;
D O I
10.3390/gels10070461
中图分类号
O63 [高分子化学(高聚物)];
学科分类号
070305 ; 080501 ; 081704 ;
摘要
Biomechanical tests typically involve bending, compression, or shear stress, while fall tests are less common. The main challenge in performing fall tests is the non-reproducible directionality of bone when tested with soft tissue. Upon removal of the soft tissue, the explanted bone's resistance to impact diminishes. Therefore, ballistic gels can fix specimens in reproducible directions and simulate periosteal soft tissue. However, the use of ballistic gels in biomechanical studies is neither standardized nor widespread. This study aimed to optimize a ballistic gel consistency that mimics the upper thigh muscle in sheep. Our results suggest a standardized and flexible evaluation method by embedding samples in ballistic gel. Compression tests were conducted using cylindrical pieces of gluteal muscle from sheep. Various compositions of agarose and gelatin mixtures were tested to achieve a muscle-like consistency. The muscle-equivalent ballistic gel was found to consist of 29.5% gelatin and 0.35% agarose. Bones remained stable within the ballistic gel setup after freeze-thaw cycles between -20 degrees C and +20 degrees C. This method reduces the variability caused by muscle and improves storage quality, allowing for tests to be conducted under consistent conditionsBallistic gels of agarose and gelatin are suitable for bone fracture models. They have muscle-like strength, fix fractures simultaneously, are inexpensive to produce, and can be stored to allow repeated measurements of the same object with changing questions.
引用
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页数:15
相关论文
共 39 条
  • [1] Abdel MP, 2016, BONE JOINT J, V98B, P461, DOI [10.1302/0301-620X.98B4.37201, 10.1302/0301-620X.98B4]
  • [2] A new metaphyseal bone defect model in osteoporotic rats to study biomaterials for the enhancement of bone healing in osteoporotic fractures
    Alt, Volker
    Thormann, Ulrich
    Ray, Seemun
    Zahner, Daniel
    Duerselen, Lutz
    Lips, Katrin
    El Khassawna, Thaqif
    Heiss, Christian
    Riedrich, Alina
    Schlewitz, Gudrun
    Ignatius, Anita
    Kampschulte, Marian
    von Dewitz, Helena
    Heinemann, Sascha
    Schnettler, Reinhard
    Langheinrich, Alexander
    [J]. ACTA BIOMATERIALIA, 2013, 9 (06) : 7035 - 7042
  • [3] Death and non-lethal weapons: A case of homicide by penetrating injury without projectile
    Borges, J.
    Sautier, C.
    Krebs-Drouot, L.
    Henry, P.
    Paysant, F.
    Scolan, V.
    [J]. FORENSIC SCIENCE INTERNATIONAL, 2022, 337
  • [4] Rib fractures prediction method for kinetic energy projectile impact: from blunt ballistic experiments on SEBS gel to impact modeling on a human torso FE model
    Bracq, A.
    Delille, R.
    Marechal, C.
    Bourel, B.
    Roth, S.
    Mauzac, O.
    [J]. FORENSIC SCIENCE INTERNATIONAL, 2019, 297 : 177 - 183
  • [5] Refrigeration and freezing of porcine tissue does not affect the retardation of fragment simulating projectiles
    Breeze, J.
    Carr, D. J.
    Mabbott, A.
    Beckett, S.
    Clasper, J. C.
    [J]. JOURNAL OF FORENSIC AND LEGAL MEDICINE, 2015, 32 : 77 - 83
  • [6] Experimental penetration of fragment simulating projectiles into porcine tissues compared with simulants
    Breeze, J.
    Hunt, N.
    Gibb, I.
    James, G.
    Hepper, A.
    Clasper, J.
    [J]. JOURNAL OF FORENSIC AND LEGAL MEDICINE, 2013, 20 (04) : 296 - 299
  • [7] Perforation of fragment simulating projectiles into goat skin and muscle
    Breeze, Johno
    James, G. R.
    Hepper, A. E.
    [J]. JOURNAL OF THE ROYAL ARMY MEDICAL CORPS, 2013, 159 (02) : 84 - 89
  • [8] Burgbacher F., 2014, P DTSCH K ORTH UNF D
  • [9] The ballistic performance of bone when impacted by fragments
    Caister, A. J.
    Carr, D. J.
    Campbell, P. D.
    Brock, F.
    Breeze, J.
    [J]. INTERNATIONAL JOURNAL OF LEGAL MEDICINE, 2020, 134 (04) : 1387 - 1393
  • [10] The use of gelatine in wound ballistics research
    Carr, D. J.
    Stevenson, T.
    Mahoney, P. F.
    [J]. INTERNATIONAL JOURNAL OF LEGAL MEDICINE, 2018, 132 (06) : 1659 - 1664