A case report of interstitial pneumonia induced by vedolizumab in a patient with ulcerative colitis

被引：0
|
作者：
Liu, Ailing [1 ]
Ye, Susu [2 ]
Diao, Zeyuan [1 ]
Liu, Hua [1 ]
Xu, Yonghong [1 ]
Wu, Jun [1 ]
Mao, Tao [1 ]
Tian, Zibin [1 ]
Ding, Xueli [1 ]
机构：
[1] Qingdao Univ, Dept Gastroenterol, Affiliated Hosp, 16 Jiangsu Rd, Qingdao 266003, Shandong Provin, Peoples R China
[2] Qingdao Univ, Liver Dis Ctr, Affiliated Hosp, Qingdao, Peoples R China
来源：
MEDICINE | 2024年 / 103卷 / 31期
关键词：
interstitial pneumonia; ulcerative colitis; vedolizumab;
D O I：
10.1097/MD.0000000000039195
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Rationale:The interstitial pneumonia (IP) linked to vedolizumab (VDZ) in patients with ulcerative colitis (UC) is rare. Prompt diagnosis and treatment can improve patient outcomes.Patient concerns:A 39-year-old man with UC who received VDZ as sole therapy developed symptoms such as chest tightness, cough, and suffocation.Diagnoses:IP was confirmed through pulmonary function tests, chest computed tomography, and bronchoscopic biopsy.Interventions:The patient was given methylprednisolone and VDZ cessation.Outcomes:The patient's symptoms improved and remained symptom-free after nearly 2 years.Lessons:VDZ-induced IP should be considered when evaluating pulmonary infections in UC patients treated with VDZ.
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页数：2
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