Alkaloids from the seeds of Peganum harmala and their chemotaxonomic significance

被引:0
|
作者
Li, Xiaojun [1 ]
Zhao, Xue [1 ]
Liu, Zhe [1 ]
Xia, Yifan [1 ]
Li, Yansong [1 ]
Dong, Hongjing [2 ,3 ]
Fang, Lei [1 ,4 ]
机构
[1] Univ Jinan, Sch Biol Sci & Technol, Jinan 250012, Peoples R China
[2] Qilu Univ Technol, Shandong Acad Sci, Shandong Anal & Test Ctr, Key Lab Appl Technol Sophisticated Analyt Instrume, Jinan 250014, Peoples R China
[3] Qilu Univ Technol, Shandong Acad Sci, Sch Pharmaceut Sci, Key Lab Nat Act Pharmaceut Constituents Res Univ S, Jinan 250014, Peoples R China
[4] Shandong Engn Res Ctr Key Technol High Value & Hig, Linyi 273399, Peoples R China
基金
中国国家自然科学基金;
关键词
Peganum; Peganum harmala; Zygophyllaceae; Alkaloids; Chemotaxonomy; CHEMICAL-CONSTITUENTS; QUINAZOLINE ALKALOIDS; METABOLITES;
D O I
10.1016/j.bse.2024.104884
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
A phytochemical study on the seeds of Peganum harmala led to the separation of 22 alkaloids, including quinazoline alkaloids (1-10), /3-carboline alkaloids (11-18), and others alkaloids (19-22). Their structures were identified by comprehensive spectroscopic analysis and comparison with literature data. Compounds 14 and 20-22 were first isolated from Zygophyllaceae family. Compounds 8 and 15 were firstly discovered as natural products. Moreover, the chemotaxonomic significance of the isolated alkaloids is discussed.
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页数:5
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