ONE POT SYNTHESIS OF ISOXAZOLONE DERIVATIVES USING IONIC LIQUID AS AN EFFICIENT CATALYST VIA MULTICOMPONENT REACTION

被引：0
作者：
Mokal, Ramesh A. [1 ]
Jadhavar, Suresh C. [1 ]
机构：
[1] Dr Babasaheb Ambedkar Marathwada Univ, Dept Chem, Yogeshwari Mahavidyalaya, Aurangabad, MH, India
来源：
HETEROCYCLIC LETTERS | 2024年 / 14卷 / 03期
关键词：
: Aryl aldehyde; ethyl acetoacetate; ionic liquid; BMIM][PF6; 6; isoxazolone; multicomponent reaction; etc; 3-COMPONENT SYNTHESIS; GREEN SYNTHESIS; ISOXAZOLE-5(4H)-ONES;
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A simple and convenient route for the synthesis of isoxazol-5(4H)-one H )-one derivatives is described via multi-component condensation of aryl aldehyde, ethyl acetoacetate and hydroxyl amine under the influence of 1-butyl-3-methyl-imidazolium hexafluoro phosphate [BMIM][PF6] 6 ] ionic liquid as an efficient, cheaper and eco-friendly catalyst under conventional reflux condition in ethanol. The present protocol has several beneficial things such as simple work-up process, a cleaner reaction, optimum reaction time and good to excellent yields.
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页码：545 / 551
页数：7
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