Design and In Vitro Testing of Pulsatile Varying Speed Controller for Continuous-Flow Left Ventricular Assist Device

被引：0
作者：
Liu, Hongtao [1 ]
Wang, Wencheng [1 ]
Zhao, Sipeng [2 ]
Xing, Fayu [1 ]
Zhang, Yunpeng [3 ]
Wu, Xiaojin [1 ]
He, Tao [4 ]
机构：
[1] Weifang Univ, Sch Machinery & Automat, Weifang 261061, Peoples R China
[2] State Grid Liaocheng Power Supply Co, Liaocheng 252000, Peoples R China
[3] Shandong Univ, Sch Elect Engn, Jinan 250061, Peoples R China
[4] Qingdao Municipal Hosp Grp, Dept Cardiol, Qingdao 266071, Peoples R China
来源：
IEEE SENSORS JOURNAL | 2024年 / 24卷 / 13期
关键词：
Pulse width modulation; Presses; Blood flow; Software; Switches; Pumps; Printed circuits; Controller design; feasibility; in vitro testing; pulsatile varying speed; pulsatility; ROTATIONAL SPEED; ARTERIAL PULSATILITY; MODULATION; IMPROVEMENT; PRESSURE; MODEL; PULSE;
D O I：
10.1109/JSEN.2024.3401680
中图分类号：
TM [电工技术]; TN [电子技术、通信技术];
学科分类号：
0808 ; 0809 ;
摘要：
The varying speed support for continuous-flow left ventricular assist device (CFLVAD) is a feasible solution to improve blood flow pulsatility in patients. This study aimed to design a pulsatile varying speed controller (PVSC) for CFLVADs and test the PVSC in vitro. Based on the pulsewidth modulation (PWM) speed regulation method, the basic principle of CFLVAD pulsatile varying speed was elaborated in detail. The PVSC was designed and manufactured by combining software and hardware. The in vitro flow loop rig was built as the test platform for PVSC. Constant and varying speed experiments were designed to test the feasibility of PVSC. The blood flow pulsation experiment was designed to study the control factors affecting blood flow pulsatility. The experimental results showed that the designed PVSC could control the rotary pump to operate reliably in both constant speed and varying speed modes. Also, the mean pump speed played a role in regulating the mean aortic pressure and flow, and the pump speed amplitude and the modulation frequency jointly affected the blood flow pulsatility.
引用
收藏
页码：21500 / 21510
页数：11
相关论文
共 32 条
  • [1] Electrocardiogram-Synchronized Rotational Speed Change Mode in Rotary Pumps Could Improve Pulsatility
    Ando, Masahiko
    Nishimura, Takashi
    Takewa, Yoshiaki
    Yamazaki, Kenji
    Kyo, Shunei
    Ono, Minoru
    Tsukiya, Tomonori
    Mizuno, Toshihide
    Taenaka, Yoshiyuki
    Tatsumi, Eisuke
    [J]. ARTIFICIAL ORGANS, 2011, 35 (10) : 941 - 947
  • [2] Pulsatile support using a rotary left ventricular assist device with an electrocardiography-synchronized rotational speed control mode for tracking heart rate variability
    Arakawa, Mamoru
    Nishimura, Takashi
    Takewa, Yoshiaki
    Umeki, Akihide
    Ando, Masahiko
    Kishimoto, Yuichiro
    Kishimoto, Satoru
    Fujii, Yutaka
    Date, Kazuma
    Kyo, Shunei
    Adachi, Hideo
    Tatsumi, Eisuke
    [J]. JOURNAL OF ARTIFICIAL ORGANS, 2016, 19 (02) : 204 - 207
  • [3] Why pulsatility still matters: a review of current knowledge
    Baric, Davor
    [J]. CROATIAN MEDICAL JOURNAL, 2014, 55 (06) : 609 - 620
  • [4] In vivo assessment of a rotary left ventricular assist device-induced artificial pulse in the proximal and distal aorta
    Bourque, Kevin
    Dague, Charles
    Farrar, David
    Harms, Kelly
    Tamez, Dan
    Cohn, William
    Tuzun, Egemeun
    Poirier, Victor
    Frazier, O. Howard
    [J]. ARTIFICIAL ORGANS, 2006, 30 (08) : 638 - 642
  • [5] IN-SILICO MODELING OF LEFT VENTRICLE TO SIMULATE DILATED CARDIOMYOPATHY AND CF-LVAD SUPPORT
    Bozkurt, Selim
    [J]. JOURNAL OF MECHANICS IN MEDICINE AND BIOLOGY, 2017, 17 (02)
  • [6] Arterial pulsatility under phasic left ventricular assist device support
    Bozkurt, Selim
    van Tuijl, Sjoerd
    van de Vosse, Frans N.
    Rutten, Marcel C. M.
    [J]. BIO-MEDICAL MATERIALS AND ENGINEERING, 2016, 27 (05) : 451 - 460
  • [7] Enhancement of Arterial Pressure Pulsatility by Controlling Continuous-Flow Left Ventricular Assist Device Flow Rate in Mock Circulatory System
    Bozkurt, Selim
    van de Vosse, Frans N.
    Rutten, Marcel C. M.
    [J]. JOURNAL OF MEDICAL AND BIOLOGICAL ENGINEERING, 2016, 36 (03) : 308 - 315
  • [8] Physiologic outcome of varying speed rotary blood pump support algorithms: a review study
    Bozkurt, Selim
    [J]. AUSTRALASIAN PHYSICAL & ENGINEERING SCIENCES IN MEDICINE, 2016, 39 (01) : 13 - 28
  • [9] Improving arterial pulsatility by feedback control of a continuous flow left ventricular assist device via in silico modeling
    Bozkurt, Selim
    van de Vosse, Frans N.
    Rutten, Marcel C. M.
    [J]. INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS, 2014, 37 (10) : 773 - 785
  • [10] Arterial pulsatility improvement in a feedback-controlled continuous flow left ventricular assist device: An ex-vivo experimental study
    Bozkurt, Selim
    van Tuijl, Sjoerd
    Schampaert, Stephanie
    van de Vosse, Frans N.
    Rutten, Marcel C. M.
    [J]. MEDICAL ENGINEERING & PHYSICS, 2014, 36 (10) : 1288 - 1295
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