Alterations in exocrine pancreatic function after acute pancreatitis

被引：3

作者：

Bejjani, Joseph ^{[1
]}

Ramsey, Mitchell L. ^{[1
]}

Lee, Peter J. ^{[1
]}

Phillips, Anna Evans ^{[2
]}

Singh, Vikesh K. ^{[3
]}

Yadav, Dhiraj ^{[2
]}

Papachristou, Georgios I. ^{[1
]}

Hart, Phil A. ^{[1
]}

机构：

[1] Ohio State Univ, Wexner Med Ctr, Div Gastroenterol Hepatol & Nutr, Columbus, OH 43210 USA

[2] Univ Pittsburgh, Med Ctr, Div Gastroenterol, Pittsburgh, PA USA

[3] Johns Hopkins Med Inst, Div Gastroenterol, Baltimore, MD USA

来源：

PANCREATOLOGY | 2024年 / 24卷 / 04期

关键词：

Exocrine pancreatic insufficiency; Exocrine pancreatic dysfunction; Pancreatic enzymes; TRANSMEMBRANE CONDUCTANCE REGULATOR; FECAL ELASTASE-1 DETERMINATION; DIABETES-MELLITUS; FLUID RESUSCITATION; STELLATE CELLS; ACINAR-CELL; INSUFFICIENCY; PREVALENCE; NECROSIS; DISEASES;

D O I：

10.1016/j.pan.2024.03.003

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Exocrine pancreatic dysfunction (EPD) is a malabsorptive complication of pancreatic disorders that can lead to a host of symptoms ranging from flatulence to diarrhea and contribute to weight loss and metabolic bone disease. It is increasingly recognized to occur after acute pancreatitis (AP), including episodes with mild severity. The risk of developing EPD after AP is influenced by a range of factors, including the degree of acinar cell destruction and inflammation during AP, and persistent structural derangements following AP. In this article, we discuss the epidemiology, pathophysiology, and clinical management of EPD after AP while highlighting key knowledge gaps. (c) 2024 The Authors. Published by Elsevier B.V. on behalf of IAP and EPC. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

引用

页码：505 / 510

页数：6

共 75 条

[51] Abstinence after First Acute Alcohol-Associated Pancreatitis Protects Against Recurrent Pancreatitis and Minimizes the Risk of Pancreatic Dysfunction [J].