Photochemical Michael Addition of Indoles to α,β-Unsaturated Ketones utilizing Arylazo Sulfones as the Photoacid Generators

被引:3
作者
Galathri, Eirini M. [1 ]
Di Terlizzi, Lorenzo [2 ]
Fagnoni, Maurizio [2 ]
Protti, Stefano [2 ]
Kokotos, Christoforos G. [1 ]
机构
[1] Natl & Kapodistrian Univ Athens, Dept Chem, Lab Organ Chem, Athens 15771, Greece
[2] Univ Pavia, Dept Chem, PhotoGreen Lab, Viale Taramelli 12, I-27100 Pavia, Italy
关键词
photoacid generators (PAGs); photochemistry; Michael addition; alpha; beta-unsaturated ketones; arylazo sulfones; FRIEDEL-CRAFTS ALKYLATION; CATALYZED CONJUGATE ADDITION; IONIC LIQUID; HETEROGENEOUS CATALYST; ACIDS; HYDROACYLATION; LACTONES; WATER;
D O I
10.1002/cctc.202400686
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
The Michael-type addition of indoles represents one of the most important C-C bonds forming reactions at their C-3 position. Herein, we present a mild, versatile and sustainable protocol for the efficient preparation of beta-indolylketones via a Michael addition between indoles and chalcones or alpha,beta-unsaturated ketones in the presence of substituted arylazo sulfones as photoacid generators (PAGs).
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页数:5
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