Continuous glucose monitoring versus conventional glucose monitoring in the ICU: A randomized controlled trial

被引:1
作者
Chu, Chen [1 ]
Li, Jian [2 ,3 ]
Yang, XiaoDong [1 ]
Zhao, HuiJing [1 ]
Wu, ZaiXian [1 ]
Xu, RuoXin [1 ]
Gao, JianLing [1 ,4 ]
机构
[1] Soochow Univ, Affiliated Hosp 4, Dept Crit Care Med, 9 Chongwen Rd, Suzhou 215124, Jiangsu, Peoples R China
[2] Soochow Univ, Affiliated Hosp 4, Dept Anesthesiol, Suzhou, Jiangsu, Peoples R China
[3] Soochow Univ, Affiliated Hosp 1, Dept Anesthesiol, Suzhou, Jiangsu, Peoples R China
[4] Soochow Univ, Affiliated Hosp 1, Dept Intens Care Unit Anesthesia, Suzhou, Jiangsu, Peoples R China
关键词
Continuous glucose monitoring system; Glycemic variability; Intensive care unit; Mortality; INTENSIVE INSULIN THERAPY; INFUSION PROTOCOL; GLYCEMIC CONTROL; ILL PATIENTS; VARIABILITY; MORTALITY;
D O I
10.1016/j.jcrc.2024.154894
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Purpose: This study evaluated the clinical utility of continuous glucose monitoring system (CGMS) in critically ill patients. Methods: In this randomized controlled trial, we randomly assigned critically ill participants with diabetes or stress-induced hyperglycemia to the CGMS group (n = 48) or to the conventional point-of-care monitoring (POCM) group (n = 48). The glucose values and clinical outcome were compared between the two group. The primary endpoint was 28-day mortality after intensive care unit admission. Results: The 28-day mortality was not significantly different between the CGMS and POCM group (20.8% vs 31.3%, P = 0.25). The mean glucose, time-weighted average glucose, glucose standard deviation and time in range (3.9-10.0) were significantly improved in the CGMS group (all P < 0.05). Conclusion: Compared with conventional POCM, CGMS did not decrease the 28-day mortality in critically ill participants with diabetes or stress-induced hyperglycemia. But CGMS may improve the glycemic control and may be increasingly used in critically ill patients.
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页数:5
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