Applications of MALDI mass spectrometry in forensic science

被引：4

作者：

de Almeida, Camila M. ^{[1
]}

dos Santos, Nayara A. ^{[1
,2
]}

Lacerda Jr, Valdemar ^{[1
]}

Ma, Xin ^{[3
]}

Fernandez, Facundo M. ^{[3
]}

Romao, Wanderson ^{[1
,2
,4
]}

机构：

[1] Univ Fed Espirito Santo UFES, Lab Petr & Forens, Av Fernando Ferrari 514, BR-29075910 Vitoria, ES, Brazil

[2] Inst Nacl Ciencia&Tecnol Forense INCT Forense, Vila Velha, Brazil

[3] Georgia Inst Technol, Sch Chem & Biochem, Atlanta, GA USA

[4] Inst Fed Espirito Santo IFES, Av Minist Salgado Filho, BR-29106010 Vila Velha, ES, Brazil

来源：

ANALYTICAL AND BIOANALYTICAL CHEMISTRY | 2024年 / 416卷 / 24期

关键词：

MALDI MSI; Forensic analysis; Fingerprints; Illicit drugs; Documentoscopy; ASSISTED-LASER-DESORPTION/IONIZATION; SINGLE HAIR SAMPLES; BALLPOINT-PEN INKS; DESORPTION IONIZATION; LATENT FINGERPRINTS; SYNTHETIC CANNABINOIDS; INFRARED-SPECTROSCOPY; QUANTITATIVE-ANALYSIS; RAMAN-SPECTROSCOPY; PLANT METABOLITES;

D O I：

10.1007/s00216-024-05470-y

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Forensic chemistry literature has grown exponentially, with many analytical techniques being used to provide valuable information to help solve criminal cases. Among them, matrix-assisted laser desorption/ionization mass spectrometry (MALDI MS), particularly MALDI MS imaging (MALDI MSI), has shown much potential in forensic applications. Due to its high specificity, MALDI MSI can analyze a wide variety of compounds in complex samples without extensive sample preparation, providing chemical profiles and spatial distributions of given analyte(s). This review introduces MALDI MS(I) to forensic scientists with a focus on its basic principles and the applications of MALDI MS(I) to the analysis of fingerprints, drugs of abuse, and their metabolites in hair, medicine samples, animal tissues, and inks in documents.

引用

页码：5255 / 5280

页数：26

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