Nonspherical Gold Nanoparticles as Bright Light Scattering Labels with Narrow Plasmon Lines

被引:0
作者
Vinokurov, Vladimir A. [1 ]
Muradov, Alexander V. [1 ]
Getmanskiy, Michael [1 ]
Qiu, Le [2 ]
Vitkin, Edward [2 ]
Itzkan, Irving [2 ]
Perelman, Lev T. [1 ,2 ]
机构
[1] Gubkin Russian State Univ Oil & Gas, Ctr Nanodiagnost, Dept Phys & Colloid Chem, Moscow 119991, Russia
[2] Harvard Univ, Beth Israel Deaconess Med Ctr, Biol & Biomed Sci Program, Ctr Adv Biomed Imaging & Photon, Boston, MA 02215 USA
来源
BIOMEDICAL APPLICATIONS OF SMART TECHNOLOGIES | 2013年 / 86卷
关键词
nanoparticle; plasmon; label; absorption; light scattering; spectroscopy; ABSORPTION;
D O I
10.4028/www.scientific.net/AST.86.51
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
In this paper we discuss the potential of nonspherical gold nanoparticles to serve as extremely bright light scattering labels for the detection of disease through several centimeters of tissue in humans in vivo. However, attempts to realize this important potential of gold nanoparticles have been limited by the broad spectroscopic linewidths usually observed. We identify the origin of this broadening as inhomogeneous broadening due to the extreme sensitivity of the surface plasmon resonance to the nanoparticle aspect ratio.
引用
收藏
页码:51 / +
页数:3
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