MazEF toxin-antitoxin systems: their role in Mycobacterium tuberculosis stress response and drug resistance

被引:0
|
作者
Thakur, Zoozeal [1 ]
Chaudhary, Renu [2 ]
Mehta, Promod K. [3 ]
机构
[1] Maharishi Markandeshwar Deemed Univ, Dept Biosci & Technol, Ambala, India
[2] CSIR Inst Genom & Integrat Biol CSIR IGIB, Struct Biol Lab, New Delhi, India
[3] Tricentenary Univ, Fac Allied Hlth Sci, Microbiol Dept, Sri Guru Gobind Singh, Gurugram, India
关键词
Anti-tubercular drugs; drug resistance; drug target; MazEF TA system; Mycobacterium tuberculosis; nutrient starvation; oxidative/nitrosative stress; persistence; toxin-antitoxin; RNA; EXPRESSION; CLEAVAGE; TARGET; LOCI;
D O I
10.1080/14787210.2024.2403021
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
引用
收藏
页码:921 / 924
页数:4
相关论文
共 50 条
  • [21] PCR Development for Analysis of Some Type II Toxin-Antitoxin Systems, relJK, mazEF3, and vapBC3 Genes, in Mycobacterium tuberculosis and Mycobacterium bovis
    Shafipour, Maryam
    Mohammadzadeh, Abdolmajid
    Ghaemi, Ezzat Allah
    Mahmoodi, Pezhman
    CURRENT MICROBIOLOGY, 2024, 81 (03)
  • [22] Prokaryotic toxin-antitoxin stress response loci
    Gerdes, K
    Christensen, SK
    Lobner-Olesen, A
    NATURE REVIEWS MICROBIOLOGY, 2005, 3 (05) : 371 - 382
  • [23] Deinococcus radiodurans Toxin-Antitoxin MazEF-dr Mediates Cell Death in Response to DNA Damage Stress
    Li, Tao
    Weng, Yulan
    Ma, Xiaoqiong
    Tian, Bing
    Dai, Shang
    Jin, Ye
    Liu, Mengjia
    Li, Jiulong
    Yu, Jiangliu
    Hua, Yuejin
    FRONTIERS IN MICROBIOLOGY, 2017, 8
  • [24] Toxin-antitoxin systems and their role(s) in persistence
    Page, Rebecca
    Peti, Wolfgang
    FASEB JOURNAL, 2015, 29
  • [25] Toxin-Antitoxin Systems of Mycobacterium smegmatis Are Essential for Cell Survival
    Frampton, Rebekah
    Aggio, Raphael B. M.
    Villas-Boas, Silas G.
    Arcus, Vickery L.
    Cook, Gregory M.
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2012, 287 (08) : 5340 - 5356
  • [26] Proteomic Profiling of Mycobacterium tuberculosis Identifies Nutrient-starvation-responsive Toxin-antitoxin Systems
    Albrethsen, Jakob
    Agner, Jeppe
    Piersma, Sander R.
    Hojrup, Peter
    Pham, Thang V.
    Weldingh, Karin
    Jimenez, Connie R.
    Andersen, Peter
    Rosenkrands, Ida
    MOLECULAR & CELLULAR PROTEOMICS, 2013, 12 (05) : 1180 - 1191
  • [27] The MazEF Toxin-Antitoxin System Alters the β-Lactam Susceptibility of Staphylococcus aureus
    Schuster, Christopher F.
    Mechler, Lukas
    Nolle, Nicoletta
    Krismer, Bernhard
    Zelder, Marc-Eric
    Goetz, Friedrich
    Bertram, Ralph
    PLOS ONE, 2015, 10 (05):
  • [28] The mazEF toxin-antitoxin system as a novel antibacterial target in Acinetobacter baumannii
    Ghafourian, Sobhan
    Good, Liam
    Sekawi, Zamberi
    Hamat, Rukman Awang
    Soheili, Sara
    Sadeghifard, Nourkhoda
    Neela, Vasanthakumari
    MEMORIAS DO INSTITUTO OSWALDO CRUZ, 2014, 109 (04): : 502 - 505
  • [29] Structural and functional analysis of the Klebsiella pneumoniae MazEF toxin-antitoxin system
    Jin, Chenglong
    Kang, Sung-Min
    Kim, Do-Hee
    Lee, Bong-Jin
    IUCRJ, 2021, 8 : 362 - 371
  • [30] Genetic systems of toxin-antitoxin as modules responsible for stress
    Klimina, K. M.
    Kyasova, D. H.
    Poluektova, E. U.
    Danilenko, V. N.
    FEBS JOURNAL, 2013, 280 : 228 - 229