MazEF toxin-antitoxin systems: their role in Mycobacterium tuberculosis stress response and drug resistance

被引:0
|
作者
Thakur, Zoozeal [1 ]
Chaudhary, Renu [2 ]
Mehta, Promod K. [3 ]
机构
[1] Maharishi Markandeshwar Deemed Univ, Dept Biosci & Technol, Ambala, India
[2] CSIR Inst Genom & Integrat Biol CSIR IGIB, Struct Biol Lab, New Delhi, India
[3] Tricentenary Univ, Fac Allied Hlth Sci, Microbiol Dept, Sri Guru Gobind Singh, Gurugram, India
关键词
Anti-tubercular drugs; drug resistance; drug target; MazEF TA system; Mycobacterium tuberculosis; nutrient starvation; oxidative/nitrosative stress; persistence; toxin-antitoxin; RNA; EXPRESSION; CLEAVAGE; TARGET; LOCI;
D O I
10.1080/14787210.2024.2403021
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
引用
收藏
页码:921 / 924
页数:4
相关论文
共 50 条
  • [1] Deciphering the role of VapBC toxin-antitoxin systems in Mycobacterium tuberculosis stress adaptation
    Thakur, Zoozeal
    Chaudhary, Renu
    Mehta, Promod K.
    FUTURE MICROBIOLOGY, 2024, 19 (18) : 1587 - 1599
  • [2] Multiple Toxin-Antitoxin Systems in Mycobacterium tuberculosis
    Sala, Ambre
    Bordes, Patricia
    Genevaux, Pierre
    TOXINS, 2014, 6 (03): : 1002 - 1020
  • [3] Functional and Biochemical Characterization of the MazEF6 Toxin-Antitoxin System of Mycobacterium tuberculosis
    Chattopadhyay, Gopinath
    Bhasin, Munmun
    Ahmed, Shahbaz
    Gosain, Tannu Priya
    Ganesan, Srivarshini
    Das, Sayan
    Thakur, Chandrani
    Chandra, Nagasuma
    Singh, Ramandeep
    Varadarajan, Raghavan
    JOURNAL OF BACTERIOLOGY, 2022, 204 (04)
  • [4] Addiction of toxin-antitoxin systems to a chaperone in Mycobacterium tuberculosis
    Bordes, Patricia
    Genevaux, Pierre
    M S-MEDECINE SCIENCES, 2017, 33 (05): : 486 - 488
  • [5] Toxin-antitoxin systems and regulatory mechanisms in Mycobacterium tuberculosis
    Slayden, Richard A.
    Dawson, Clinton C.
    Cummings, Jason E.
    PATHOGENS AND DISEASE, 2018, 76 (04):
  • [6] Control of Toxin-Antitoxin Systems by Proteases in Mycobacterium Tuberculosis
    Bordes, Patricia
    Genevaux, Pierre
    FRONTIERS IN MOLECULAR BIOSCIENCES, 2021, 8
  • [7] Toxin-antitoxin systems shows variability among Mycobacterium tuberculosis lineages
    Solano-Gutierrez, J. S.
    Pino, C.
    Robledo, J.
    FEMS MICROBIOLOGY LETTERS, 2019, 366 (01)
  • [8] Computational insights into promoter architecture of toxin-antitoxin systems of Mycobacterium tuberculosis
    Thakur, Zoozeal
    Saini, Vandana
    Arya, Preeti
    Kumar, Ajit
    Mehta, Promod K.
    GENE, 2018, 641 : 161 - 171
  • [9] MazEF Toxin-Antitoxin System-Mediated DNA Damage Stress Response in Deinococcus radiodurans
    Dai, Jingli
    Chen, Zijing
    Hou, Jinfeng
    Wang, Yudong
    Guo, Miao
    Cao, Jiajia
    Wang, Liangyan
    Xu, Hong
    Tian, Bing
    Zhao, Ye
    FRONTIERS IN GENETICS, 2021, 12
  • [10] TOXIN-ANTITOXIN SYSTEMS AND MYCOBACTERIUM ABSCESSUS PERSISTENCE
    Weiland, H.
    Chauhan, U.
    Barth, V. C.
    Woychik, N. A.
    PEDIATRIC PULMONOLOGY, 2019, 54 : S274 - S274