Advances, challenges and future directions in the development of in vitro gastrointestinal models used in assessing infant formulas

被引：0
作者：
Wang, Ni [1 ]
Duan, Sufang [2 ,3 ]
Wu, Peng [1 ]
Liu, Biao [3 ]
Ye, Wenhui [3 ]
He, Jian [2 ,4 ]
Szeto, Ignatius Man-Yau [2 ,4 ]
Chen, Xiao Dong [1 ]
机构：
[1] Soochow Univ, Coll Chem Chem Engn & Mat Sci, Sch Chem & Environm Engn, Life Qual Engn Interest Grp, Suzhou 215123, Peoples R China
[2] Inner Mongolia Dairy Technol Res Inst Co Ltd, Hohhot 010110, Peoples R China
[3] Inner Mongolia Yili Ind Grp Co Ltd, Yili Maternal & Infant Nutr Inst YMINI, Beijing 100070, Peoples R China
[4] Natl Ctr Technol Innovat Dairy, Hohhot 010110, Peoples R China
来源：
INTERNATIONAL JOURNAL OF DAIRY TECHNOLOGY | 2024年 / 77卷 / 04期
关键词：
In vitro gastrointestinal models; Infant formula; Digestion; Absorption; Fermentation; Whole-process; HUMAN-MILK; PROTEIN DIGESTIBILITY; BIOACTIVE PEPTIDES; ORAL ABSORPTION; GUT MICROBIOTA; DIGESTION; BIOAVAILABILITY; PREBIOTICS; PROBIOTICS; FOOD;
D O I：
10.1111/1471-0307.13130
中图分类号：
TS2 [食品工业];
学科分类号：
0832 ;
摘要：
This review critically evaluates current in vitro gastrointestinal models for assessing infant formulas from a perspective focusing on a process along digestion, absorption and microbial fermentation. Despite their potential, none of the current in vitro gastrointestinal models fully considers the dynamics and continuous upstream-downstream process of the human digestive tract. Considering the substantial differences between infants and adults, there is a pressing need for whole-process gastrointestinal models tailored to infants. Developing such models is crucial for accurately assessing infant formula nutritional value and physiological function, enhancing the formulation of infant formulas to better meet the needs of infants.
引用
收藏
页码：1044 / 1061
页数：18
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