Development of oculomics artificial intelligence for cardiovascular risk factors: A case study in fundus oculomics for HbA1c assessment and clinically relevant considerations for clinicians

被引：1

作者：

Ong, Joshua ^{[1
]}

Jang, Kuk Jin ^{[2
]}

Baek, Seung Ju ^{[5
]}

Hu, Dongyin ^{[2
]}

Lin, Vivian ^{[2
]}

Jang, Sooyong ^{[2
]}

Thaler, Alexandra ^{[3
]}

Sabbagh, Nouran ^{[3
]}

Saeed, Almiqdad ^{[3
,4
]}

Kwon, Minwook ^{[5
]}

Kim, Jin Hyun ^{[6
]}

Lee, Seongjin ^{[5
]}

Han, Yong Seop ^{[7
]}

Zhao, Mingmin ^{[2
]}

Sokolsky, Oleg ^{[2
]}

Lee, Insup ^{[2
]}

Al-Aswad, Lama A. ^{[2
,3
]}

机构：

[1] Univ Michigan, Kellogg Eye Ctr, Dept Ophthalmol & Visual Sci, Ann Arbor, MI USA

[2] Univ Penn, Sch Engn & Appl Sci, Philadelphia, PA 19104 USA

[3] Univ Penn, Perelman Sch Med, Scheie Eye Inst, Dept Ophthalmol, Philadelphia, PA 19104 USA

[4] St John Eye Hosp Jerusalem, Dept Ophthalmol, Jerusalem, Israel

[5] Dept AI Convergence Engn, Jinju, South Korea

[6] Dept Intelligence & Commun Engn, Jinju, South Korea

[7] Gyeongsang Natl Univ, Coll Med, Inst Hlth Sci, Dept Ophthalmol, Jinju, South Korea

来源：

ASIA-PACIFIC JOURNAL OF OPHTHALMOLOGY | 2024年 / 13卷 / 04期

关键词：

Artificial intelligence; Reliability; Trustworthy; Ophthalmology; Oculomics; Machine learning; PHOTOGRAPHS; PREDICTION; BIOMARKERS; MODELS;

D O I：

10.1016/j.apjo.2024.100095

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Artificial Intelligence (AI) is transforming healthcare, notably in ophthalmology, where its ability to interpret images and data can significantly enhance disease diagnosis and patient care. Recent developments in oculomics, the integration of ophthalmic features to develop biomarkers for systemic diseases, have demonstrated the potential for providing rapid, non-invasive methods of screening leading to enhance in early detection and improve healthcare quality, particularly in underserved areas. However, the widespread adoption of such AI-based technologies faces challenges primarily related to the trustworthiness of the system. We demonstrate the potential and considerations needed to develop trustworthy AI in oculomics through a pilot study for HbA1c assessment using an AI-based approach. We then discuss various challenges, considerations, and solutions that have been developed for powerful AI technologies in the past in healthcare and subsequently apply these considerations to the oculomics pilot study. Building upon the observations in the study we highlight the challenges and opportunities for advancing trustworthy AI in oculomics. Ultimately, oculomics presents as a powerful and emerging technology in ophthalmology and understanding how to optimize transparency prior to clinical adoption is of utmost importance.

引用

页数：13