Recent advances in corneal neovascularization imaging

被引：0

作者：

Wen, Yinuo ^{[1
,2
,3
,4
,5
]}

Chen, Zhongxing ^{[1
,2
,3
,4
,5
]}

Mcalinden, Colm ^{[1
,2
,3
,4
,5
,6
]}

Zhou, Xingtao ^{[1
,2
,3
,4
,5
]}

Huang, Jinhai ^{[1
,2
,3
,4
,5
]}

机构：

[1] Fudan Univ, Eye & ENT Hosp, Eye Inst, 19 Baoqing Rd, Shanghai 200031, Peoples R China

[2] Fudan Univ, Eye & ENT Hosp, Dept Ophthalmol, 19 Baoqing Rd, Shanghai 200031, Peoples R China

[3] Chinese Acad Med Sci, Key Lab Myopia & Related Eye Dis, NHC, Shanghai, Peoples R China

[4] Chinese Acad Med Sci, Key Lab Myopia & Related Eye Dis, Shanghai, Peoples R China

[5] Shanghai Res Ctr Ophthalmol & Optometry, Shanghai, Peoples R China

[6] Queen Victoria Hosp, Corneo Plast Unit & Eye Bank, E Grinstead, England

来源：

EXPERIMENTAL EYE RESEARCH | 2024年 / 244卷

基金：

中国国家自然科学基金;

关键词：

Corneal neovascularization; Optical coherence tomography angiography; Anterior segment; Corneal diseases; Corneal imaging diagnosis; COHERENCE TOMOGRAPHY ANGIOGRAPHY; FINE-NEEDLE DIATHERMY; INDOCYANINE GREEN ANGIOGRAPHY; VIVO CONFOCAL MICROSCOPY; SPECTRAL-DOMAIN; QUANTITATION; VASCULATURE; FLUORESCEIN; KERATITIS; DISEASE;

D O I：

10.1016/j.exer.2024.109930

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Corneal neovascularization (CoNV) is a vision-threatening ocular disease commonly secondary to infectious, inflammatory, and traumatic etiologies. Slit lamp photography, in vivo confocal microscopy, angiography, and optical coherence tomography angiography (OCTA) are the primary diagnostic tools utilized in clinical practice to evaluate the vasculature of the ocular surface. However, there is currently a dearth of comprehensive literature that reviews the advancements in imaging technology for CoNV administration. Initially designed for retinal vascular imaging, OCTA has now been expanded to the anterior segment and has shown promising potential for imaging the conjunctiva, cornea, and iris. This expansion allows for the quantitative monitoring of the structural and functional changes associated with CoNV. In this review, we emphasize the impact of algorithm optimization in anterior segment-optical coherence tomography angiography (AS-OCTA) on the diagnostic efficacy of CoNV. Through the analysis of existing literature, animal model assessments are further reported to investigate its pathological mechanism and exhibit remarkable therapeutic interventions. In conclusion, ASOCTA holds broad prospects and extensive potential for clinical diagnostics and research applications in CoNV.

引用

页数：13

共 104 条

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