Recent advances in the synthesis of dihydropyrimidinones via biginelli reaction

被引:1
|
作者
Mushtaq, Aqsa [1 ]
Munawar, Anza [1 ]
Parveen, Bushra [1 ]
Javed, Sadia [2 ]
Zahoor, Ameer Fawad [1 ]
Ali, Kulsoom Ghulam [1 ]
Mansha, Asim [1 ]
Irfan, Ahmad [3 ]
机构
[1] Govt Coll Univ Faisalabad, Dept Chem, Faisalabad 38000, Pakistan
[2] Govt Coll Univ Faisalabad, Dept Biochem, Faisalabad 38000, Pakistan
[3] King Khalid Univ, Dept Chem, POB 9004, Abha 61413, Saudi Arabia
关键词
Biginelli reaction; Multicomponent reaction; Novel catalyst; Solvent free; ONE-POT SYNTHESIS; RECOVERABLE HETEROGENEOUS CATALYST; MICROWAVE-ASSISTED SYNTHESIS; SOLVENT-FREE; IONIC LIQUID; MULTICOMPONENT SYNTHESIS; RECYCLABLE CATALYST; ORGANIC FRAMEWORK; RAPID SYNTHESIS; SULFONIC-ACID;
D O I
10.1007/s13738-024-03100-z
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Dihydropyrimidinone skeleton (DHMP) plays a vital part in medicinal and pharmaceutical chemistry as its derivatives exhibit a broad spectrum of anti-microbial, anti-fungal, anti-bacterial, anti-inflammatory and anti-cancer activities. Taking into account the biological significance of DHPMs, organic chemists have developed different methodologies to synthesize these biologically active target molecules. Our review focuses on the one-pot synthesis of dihydropyrimidinones via Biginelli reaction by using the efficient catalysts and reaction conditions, thereby covering the literature published since 2021.
引用
收藏
页码:2565 / 2586
页数:22
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