Recent advances in cyclization reactions via catalytic allylic substitution for the asymmetric synthesis of heterocyclic compounds

被引：5

作者：

Pan, Bendu ^{[1
]}

Reddy, Chitreddy V. Subba ^{[1
]}

Wu, Yunru ^{[1
]}

Qiu, Liqin ^{[1
]}

机构：

[1] Sun Yat Sen Univ, Sch Chem, Guangdong Key Lab Chiral Mol & Drug Discovery, IGCME, Guangzhou 510006, Peoples R China

来源：

TETRAHEDRON LETTERS | 2024年 / 141卷

关键词：

Cyclization reactions; Allylic substitution; Asymmetric synthesis; Heterocyclic compounds; ATROPISOMERIC MONOPHOSPHINE LIGANDS; ENANTIOSELECTIVE SYNTHESIS; KINETIC RESOLUTION; ALKYLATION; PD; ETHERIFICATION; ALLYLATION; EFFICIENT; AMINATION; ENANTIO;

D O I：

10.1016/j.tetlet.2024.155071

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The role of allylic substitution reactions is crucial in organic synthesis. Through these reactions, the development of numerous molecular structures with a wide range of applications can be achieved in diverse fields. They also provide an efficient methodology for synthesizing novel heterocyclic compounds with potential as drugs, natural products, and bioactive structures. This review summarizes the research progress in cyclization reactions via catalytic allylic substitution for the asymmetric synthesis of heterocyclic compounds over the past five years. The discussion focused on catalytic asymmetric allylic substitutions with nitrogen, oxygen and carbon nucleophiles.

引用

页数：10

共 131 条

[1]

Al-Harbi A., 2015, Eur. J. Chem., V6, P63

[2] ZrOCl2•8H2O: An Efficient, Ecofriendly, and Recyclable Catalyst for Ultrasound-Accelerated, One-Pot, Solvent-Free Synthesis of 8-Aryl-7,8-dihydro-[1,3]dioxolo[4,5-g]quinolin-6-(5H)-one and 4-Aryl-3,4-dihydroquinolin-2(1H)-one Derivatives [J].