Langerhans cell histiocytosis of the suprasellar region: diagnosis based on thyroid cytology

被引:0
|
作者
Mavromati, Maria [1 ,2 ]
Caironi, Verdiana [3 ]
Saiji, Essia [2 ,4 ]
Vargas, Maria-Isabel [2 ,5 ]
Momjian, Shahan [2 ,6 ]
Andrade-Lopes, Stephanie [1 ]
Gubert, Capucine [7 ]
Demarchi, Marco Stefano [8 ]
Mainta, Ismini [9 ]
Jornayvaz, Francois R. [1 ,2 ]
Samii, Kaveh [2 ,10 ]
Stalder, Gregoire [11 ,12 ,13 ]
Leboulleux, Sophie [1 ,2 ]
机构
[1] Geneva Univ Hosp, Dept Endocrinol Diabetol Nutr & Therapeut Educ, Rue Gabrielle Perret Gentil, Geneva, Switzerland
[2] Univ Geneva, Fac Med, Rue Michel Servet 1, CH-1211 Geneva, Switzerland
[3] Ente Osped Cantonale, Lugano Reg Hosp, Dept Internal Med, Via Tesserete Lugano, Bellinzona, Switzerland
[4] Univ Geneva, Geneva Univ Hosp, Dept Pathol, Rue Gabrielle Perret Gentil, Geneva, Switzerland
[5] Univ Geneva, Geneva Univ Hosp, Dept Neuroradiol, Rue Gabrielle Perret Gentil, Geneva, Switzerland
[6] Univ Geneva, Geneva Univ Hosp, Dept Neurosurg, Rue Gabrielle Perret Gentil, Geneva, Switzerland
[7] Univ Geneva, Geneva Univ Hosp, Dept Internal Med, Rue Gabrielle Perret Gentil, Geneva, Switzerland
[8] Geneva Univ Hosp, Dept Thorac & Endocrine Surg, Rue Gabrielle Perret Gentil, Geneva, Switzerland
[9] Geneva Univ Hosp, Dept Nucl Med, Rue Gabrielle Perret Gentil, Geneva, Switzerland
[10] Geneva Univ Hosp, Dept Hematol, Rue Gabrielle Perret Gentil, Geneva, Switzerland
[11] Lausanne Univ Hosp, Serv & Cent Lab Hematol, rue Bugnon, Lausanne, Switzerland
[12] Hop Valais, Inst Cent Hop, Serv Hematol, Ave Grand Champsec, Sion, Switzerland
[13] Hop Valais, Inst Cent Hop, Lab Hematol, Ave Grand Champsec, Sion, Switzerland
关键词
histiocytosis; thyroid FNA; hypothalamic lesion; NEEDLE-ASPIRATION-CYTOLOGY; ADULTS; GLAND; ENDOCRINE; FEATURES;
D O I
10.1530/ETJ-24-0011
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Langerhans cell histiocytosis (LCH) may present as unifocal disease of the suprasellar region, with symptoms and signs of hypopituitarism, arginine vasopressin deficiency (AVP-D), and weight gain. Transcranial biopsy is necessary to define diagnosis and guide treatment decisions, but it is associated with significant morbidity. We describe a patient with Hashimoto thyroiditis and a single hypothalamic mass in whom LCH diagnosis was made by thyroid fine-needle aspiration cytology (FNAC) performed despite nonspecific findings in thyroid imaging, on the basis of a slightly elevated [18F]-fluorodeoxyglucose (FDG) avidity on PET/CT and volume increase during follow-up.
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页数:6
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