Langerhans cell histiocytosis of the suprasellar region: diagnosis based on thyroid cytology

被引：0

作者：

Mavromati, Maria ^{[1
,2
]}

Caironi, Verdiana ^{[3
]}

Saiji, Essia ^{[2
,4
]}

Vargas, Maria-Isabel ^{[2
,5
]}

Momjian, Shahan ^{[2
,6
]}

Andrade-Lopes, Stephanie ^{[1
]}

Gubert, Capucine ^{[7
]}

Demarchi, Marco Stefano ^{[8
]}

Mainta, Ismini ^{[9
]}

Jornayvaz, Francois R. ^{[1
,2
]}

Samii, Kaveh ^{[2
,10
]}

Stalder, Gregoire ^{[11
,12
,13
]}

Leboulleux, Sophie ^{[1
,2
]}

机构：

[1] Geneva Univ Hosp, Dept Endocrinol Diabetol Nutr & Therapeut Educ, Rue Gabrielle Perret Gentil, Geneva, Switzerland

[2] Univ Geneva, Fac Med, Rue Michel Servet 1, CH-1211 Geneva, Switzerland

[3] Ente Osped Cantonale, Lugano Reg Hosp, Dept Internal Med, Via Tesserete Lugano, Bellinzona, Switzerland

[4] Univ Geneva, Geneva Univ Hosp, Dept Pathol, Rue Gabrielle Perret Gentil, Geneva, Switzerland

[5] Univ Geneva, Geneva Univ Hosp, Dept Neuroradiol, Rue Gabrielle Perret Gentil, Geneva, Switzerland

[6] Univ Geneva, Geneva Univ Hosp, Dept Neurosurg, Rue Gabrielle Perret Gentil, Geneva, Switzerland

[7] Univ Geneva, Geneva Univ Hosp, Dept Internal Med, Rue Gabrielle Perret Gentil, Geneva, Switzerland

[8] Geneva Univ Hosp, Dept Thorac & Endocrine Surg, Rue Gabrielle Perret Gentil, Geneva, Switzerland

[9] Geneva Univ Hosp, Dept Nucl Med, Rue Gabrielle Perret Gentil, Geneva, Switzerland

[10] Geneva Univ Hosp, Dept Hematol, Rue Gabrielle Perret Gentil, Geneva, Switzerland

[11] Lausanne Univ Hosp, Serv & Cent Lab Hematol, rue Bugnon, Lausanne, Switzerland

[12] Hop Valais, Inst Cent Hop, Serv Hematol, Ave Grand Champsec, Sion, Switzerland

[13] Hop Valais, Inst Cent Hop, Lab Hematol, Ave Grand Champsec, Sion, Switzerland

来源：

EUROPEAN THYROID JOURNAL | 2024年 / 13卷 / 03期

关键词：

histiocytosis; thyroid FNA; hypothalamic lesion; NEEDLE-ASPIRATION-CYTOLOGY; ADULTS; GLAND; ENDOCRINE; FEATURES;

D O I：

10.1530/ETJ-24-0011

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Langerhans cell histiocytosis (LCH) may present as unifocal disease of the suprasellar region, with symptoms and signs of hypopituitarism, arginine vasopressin deficiency (AVP-D), and weight gain. Transcranial biopsy is necessary to define diagnosis and guide treatment decisions, but it is associated with significant morbidity. We describe a patient with Hashimoto thyroiditis and a single hypothalamic mass in whom LCH diagnosis was made by thyroid fine-needle aspiration cytology (FNAC) performed despite nonspecific findings in thyroid imaging, on the basis of a slightly elevated [18F]-fluorodeoxyglucose (FDG) avidity on PET/CT and volume increase during follow-up.

引用

页数：6

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