Preventing herpes zoster in immunocompromised patients: Current concepts

被引：4

作者：

Calabrese, Cassandra ^{[1
,2
]}

Kirchner, Elizabeth ^{[1
]}

Fernandez, James ^{[2
,3
]}

Calabrese, Leonard H. ^{[1
,2
]}

机构：

[1] Cleveland Clin, Dept Rheumatol & Immunol Dis, A50,9500 Euclid Ave, Cleveland, OH 44195 USA

[2] Case Western Reserve Univ, Cleveland Clin, Lerner Coll Med, Cleveland, OH 44195 USA

[3] Cleveland Clin, Dept Allergy & Clin Immunol, Cleveland, OH USA

来源：

CLEVELAND CLINIC JOURNAL OF MEDICINE | 2024年 / 91卷 / 07期

关键词：

SUBUNIT VACCINE; EFFICACY; RISK;

D O I：

10.3949/ccjm.91a.24019

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Herpes zoster (HZ) incidence is much higher in immunocompromised individuals than in immunocompetent individuals. HZ also occurs at a younger age and is often more severe in immunocompromised persons. Preventive strategies center around the recombinant zoster vaccine (RZV), which is approved for immunocompromised adults age 19 and older. Identifying those at greatest risk is critical. For those considering vaccination, evidence gaps regarding vaccine efficacy, toxicity, length of protection, and potential effects on underlying conditions may complicate shared and informed decision-making. Recent data have filled some of these gaps, with several societies issuing recommendations regarding vaccination. Remaining gaps are currently addressed by expert opinion.

引用

页码：437 / 445

页数：9

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