Automated and integrated ultrahigh throughput screening for industrial strain enabled by acoustic-droplet-ejection mass spectrometry

被引:0
|
作者
Zhang, Zhidan [1 ,2 ]
Zhang, Chao [2 ]
Zhang, Xu [3 ]
Chen, Jiuzhou [2 ]
Cai, Ningyun [4 ]
Zhong, Shasha [4 ]
Han, Zhibo [4 ]
Zhu, Yan [2 ]
Zheng, Ping [2 ]
Sun, Jibin [2 ]
Liu, Changxiao [1 ,5 ]
机构
[1] Shenyang Pharmaceut Univ, Sch Pharm, Shenyang 117004, Peoples R China
[2] Chinese Acad Sci, Key Lab Engn Biol Low Carbon Mfg, Syst Biol Ctr, Tech Support Core Facil,Tianjin Inst Ind Biotechno, Tianjin 300308, Peoples R China
[3] Univ Tradit Chinese Med, Inst Tradit Chinese Med, Tianjin 301617, Peoples R China
[4] Tianjin Univ Sci & Technol, Coll Biotechnol, Tianjin 300457, Peoples R China
[5] Tianjin Inst Pharmaceut Res, State Key Lab Drug Delivery & Pharmacokinet, Tianjin 300301, Peoples R China
关键词
D O I
10.1016/j.jpha.2024.02.003
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
引用
收藏
页数:3
相关论文
共 50 条
  • [31] High-Throughput Compound Quality Assessment with High-Mass-Resolution Acoustic Ejection Mass Spectrometry: An Automatic Data Processing Toolkit
    Quinn, Alandra
    Ivosev, Gordana
    Chin, Jefferson
    Mongillo, Robert
    Veiga, Cristiano
    Covey, Thomas R.
    Kapinos, Brendon
    Khunte, Bhagyashree
    Zhang, Hui
    Troutman, Matthew D.
    Liu, Chang
    ANALYTICAL CHEMISTRY, 2024, 96 (21) : 8381 - 8389
  • [32] Novel heparan sulfate assay by using automated high throughput mass spectrometry: Application to monitoring and screening for mucopolysaccharidoses
    Tomatsu, Shunji
    Shimada, Tsutomu
    LaMarr, William A.
    Vlies, Naomi V.
    Yasuda, Eriko
    Mason, Robert W.
    Kubaski, Francyne
    Giugliani, Roberto
    Yamaguchi, Seiji
    Suzuki, Yasuyuki
    Orri, Tadao
    Kubaski, Francyne
    MOLECULAR GENETICS AND METABOLISM, 2015, 114 (02) : S116 - S116
  • [33] Automated Structural Activity Screening of β-Diketonate Assemblies with High-Throughput Ion Mobility-Mass Spectrometry
    Williams, Oscar H. Lloyd
    Rusli, Olivia
    Ezzedinloo, Lida
    Dodgen, Tyren M.
    Clegg, Jack K.
    Rijs, Nicole J.
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2024, 63 (04)
  • [34] Utilising acoustic mist ionisation mass spectrometry to identify redox cycling compounds in high throughput screening outputs
    Moore, Rachel
    Molyneux, Corinne
    Sinclair, Ian
    Holdgate, Geoffrey A.
    Walsh, Jarrod
    SLAS DISCOVERY, 2022, 27 (06) : 369 - 374
  • [35] Differential Mobility Spectrometry Acoustic Ejection Mass Spectrometer System for Screening Isomerization-Mediating Enzyme Drug Targets
    Bazargan, Samad
    Dranchak, Patricia
    Liu, Chang
    Inglese, James
    Janiszewski, John
    Schneider, Bradley B.
    Covey, Thomas R.
    Analytical Chemistry, 2024, 96 (52) : 20645 - 20655
  • [36] High-Throughput Analysis from Complex Matrices: Acoustic Ejection Mass Spectrometry from Phase-Separated Fluid Samples
    Guo, Yuzhu
    Forbush, Michael
    Covey, Thomas R.
    Ghislain, Lucien
    Liu, Chang
    METABOLITES, 2021, 11 (11)
  • [37] Novel heparan sulfate assay by using automated high-throughput mass spectrometry: Application to monitoring and screening for mucopolysaccharidoses
    Shimada, Tsutomu
    Kelly, Joan
    LaMarr, William A.
    van Vlies, Naomi
    Yasuda, Eriko
    Mason, Robert W.
    Mackenzie, William
    Kubaski, Francyne
    Giugliani, Roberto
    Chinen, Yasutsugu
    Yamaguchi, Seiji
    Suzuki, Yasuyuki
    Orii, Kenji E.
    Fukao, Toshiyuki
    Orii, Tadao
    Tomatsu, Shunji
    MOLECULAR GENETICS AND METABOLISM, 2014, 113 (1-2) : 92 - 99
  • [38] Automated high-throughput colorectal cancer biomarker screening using Rapid Evaporative Ionisation Mass Spectrometry (REIMS)
    Huq, T.
    Alexander, J.
    Cameron, S.
    Takats, Z.
    Kinross, J.
    BRITISH JOURNAL OF SURGERY, 2018, 105 : 21 - 21
  • [39] Coupling Laser Diode Thermal Desorption with Acoustic Sample Deposition to Improve Throughput of Mass Spectrometry-Based Screening
    Haarhoff, Zuzana
    Wagner, Andrew
    Picard, Pierre
    Drexler, Dieter M.
    Zvyaga, Tatyana
    Shou, Wilson
    JOURNAL OF BIOMOLECULAR SCREENING, 2016, 21 (02) : 165 - 175
  • [40] Acoustic Mist Ionization-Mass Spectrometry: A Comparison to Conventional High-Throughput Screening and Compound Profiling Platforms
    Belov, Arseniy M.
    Kozole, Joseph
    Bean, Mark F.
    Machutta, Carl A.
    Zhang, Guofeng
    Gao, Enoch N.
    Ghislain, Luke
    Datwani, Sammy S.
    Leveridge, Melanie
    Annan, Roland S.
    ANALYTICAL CHEMISTRY, 2020, 92 (20) : 13847 - 13854