The Janus kinase/signal transducers and activators of transcription (JAK/ STAT) pathway contributes to the defense against bacterial infection in the pea aphid

被引：1

作者：

Zhao, Yu-Jie ^{[1
]}

Li, Yue-Ming ^{[1
]}

Yang, Ting ^{[1
]}

Lu, Zhiqiang ^{[1
]}

机构：

[1] Northwest A&F Univ, Coll Plant Protect, State Key Lab Crop Stress Resistance & High Effici, Yangling 712100, Shaanxi, Peoples R China

来源：

PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY | 2024年 / 202卷

关键词：

JAK/STAT; Acyrthosiphon pisum; Defense; Bacterial infection; RNA interference; ANTIVIRAL IMMUNITY; SIGNALING PATHWAY; PATHOGEN;

D O I：

10.1016/j.pestbp.2024.105915

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The Janus kinase/signal transducers and activators of transcription (JAK/STAT) signaling is activated by infections of bacteria, fungi, viruses and parasites and mediated cellular and humoral immune responses. In the pea aphid Acyrthosiphon pisum little is known about the function of JAK/STAT signaling in its immune system. In this study, we first showed that expression of genes in the JAK/STAT signaling, including the receptors Domeless1/2, Janus kinase (JAK) and transcriptional factor Stat92E, is up-regulated upon bacteria Escherichia coli and Staphylococcus aureus and fungus Beauveria bassiana infections. After knockdown of expression of these genes by means of dsRNA injection, the aphids harbored more bacteria and suffered more death after infected with E. coli and S. aureus, but showed no significant change after B. bassiana infection. Our study suggests the JAK/STAT signaling contributes to the defense against bacterial infection in the pea aphid.

引用

页数：7

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