Bilinguals show evidence of brain maintenance in Alzheimer's disease

被引：0
作者：
Coulter, Kristina [1 ,2 ]
Phillips, Natalie A. [1 ,2 ]
机构：
[1] Concordia Univ, Dept Psychol, Montreal, PQ, Canada
[2] Ctr Res Human Dev, Montreal, PQ, Canada
来源：
BILINGUALISM-LANGUAGE AND COGNITION | 2024年
基金：
加拿大健康研究院; 加拿大自然科学与工程研究理事会;
关键词：
bilingualism; Alzheimer's disease; brain reserve; brain maintenance; hippocampal volume; MILD COGNITIVE IMPAIRMENT; AGE; DEMENTIA; RESERVE; SEGMENTATION; 2ND-LANGUAGE; THICKNESS; DIAGNOSIS; EDUCATION; ATROPHY;
D O I：
10.1017/S1366728924000221
中图分类号：
H0 [语言学];
学科分类号：
030303 ; 0501 ; 050102 ;
摘要：
We examined brain and cognitive reserve related to bilingualism in older adults with, or at-risk for, Alzheimer's disease (AD) from the Canadian Consortium on Neurodegeneration in Aging and the Quebec Consortium for the Early Identification of Alzheimer's Disease. We used surface-based morphometry methods to measure cortical thickness and volume of language-related and AD-related brain regions. We did not observe evidence of brain reserve in language-related regions. However, reduced hippocampal volume was observed for monolingual, but not bilingual, older adults with AD. Thus, bilingualism is hypothesized to contribute to reserve in the form of brain maintenance in the context of AD.
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页数：10
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