Consumption of Phytoestrogens Affects Bone Health by Regulating Estrogen Metabolism

被引:7
作者
Tomczyk-Warunek, Agnieszka [1 ]
Winiarska-Mieczan, Anna [2 ]
Blicharski, Tomasz [3 ]
Blicharski, Rudolf [3 ]
Kowal, Filip [3 ]
Pano, Ines Torne [3 ]
Tomaszewska, Ewa [4 ]
Muszynski, Siemowit [5 ]
机构
[1] Med Univ Lublin, Dept Rehabil & Physiotherapy, Lab Locomotor Syst Res, Lublin, Poland
[2] Univ Life Sci Lublin, Inst Anim Nutr & Bromatol, Dept Bromatol & Nutr Physiol, Lublin, Poland
[3] Med Univ Lublin, Dept Orthoped & Rehabil, Lublin, Poland
[4] Univ Life Sci Lublin, Dept Anim Physiol, Lublin, Poland
[5] Univ Life Sci Lublin, Dept Biophys, Lublin, Poland
关键词
osteoporosis; estrogens; phytoestrogens; estrogen metabolism; bone health; MINERAL DENSITY; DOUBLE-BLIND; POSTMENOPAUSAL WOMEN; OXIDATIVE STRESS; VITAMIN-D; REPLACEMENT THERAPY; TURNOVER MARKERS; SOY ISOFLAVONES; RECEPTOR-ALPHA; FRACTURE RISK;
D O I
10.1016/j.tjnut.2024.05.026
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
Osteoporosis is a significant concern in bone health, and understanding its pathomechanism is crucial for developing effective prevention and treatment strategies. This article delves into the relationship between estrogen metabolism and bone mineralization, shedding light on how phytoestrogens can influence this intricate process. Estrogen, a hormone primarily associated with reproductive health, plays a pivotal role in maintaining bone density and structure. The article explores the positive effects of estrogen on bone mineralization, highlighting its importance in preventing conditions like osteoporosis. Phytoestrogens, naturally occurring compounds found in certain plant-based foods, are the focal point of the discussion. These compounds have the remarkable ability to mimic estrogen's actions in the body. The article investigates how phytoestrogens can modulate the activity of estrogen, thereby impacting bone health. Furthermore, the article explores the direct effects of phytoestrogens on bone mineralization and structure. By regulating estrogen metabolism, phytoestrogens can contribute to enhanced bone density and reduced risk of osteoporosis. Finally, the article emphasizes the role of plant-based diets as a source of phytoestrogens. By incorporating foods rich in phytoestrogens into one's diet, individuals may potentially bolster their bone health, adding a valuable dimension to the ongoing discourse on osteoporosis prevention. In conclusion, this article offers a comprehensive overview of 137 positions of literature on the intricate interplay between phytoestrogens, estrogen metabolism, and bone health, shedding light on their potential significance in preventing osteoporosis and promoting overall well-being.
引用
收藏
页码:2611 / 2627
页数:17
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