Comprehensive analysis of antibiotic and heavy metal resistance, and virulence factors in Aeromonas veronii CTe-01: Implications for global antimicrobial resistance

被引：1

作者：

Tataje-Lavanda, Luis ^{[1
,2
]}

Ormeno-Vasquez, Phillip ^{[3
]}

Choque-Guevara, Ricardo ^{[1
]}

Altamirano-Diaz, Rosa ^{[4
]}

Fernandez-Diaz, Manolo ^{[1
]}

Tantalean, Juan C. ^{[4
]}

机构：

[1] FARVET, Labs Invest & Desarrollo, Chincha Alta, Ica, Peru

[2] Univ Privada San Juan Bautista, Escuela Profes Med Humana, Lima, Peru

[3] Pontificia Univ Catolica Chile, Fac Ciencias Biol, Fac Agron & Sistemas Nat, Santiago, Chile

[4] Univ Nacl San Luis Gonzaga, Fac Ciencias Biol, Lab Biotecnol & Biol Mol, Ica, Peru

来源：

JOURNAL OF KING SAUD UNIVERSITY SCIENCE | 2024年 / 36卷 / 09期

关键词：

Aeromonas veronii; Heavy metal resistance; Antibiotic resistance; Genomics; AEROMONAS SPP; GENES; TAXONOMY;

D O I：

10.1016/j.jksus.2024.103402

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Objectives: This study aimed to characterize Aeromonas veronii CTe-01 focusing on its resistance to heavy metal and antibiotics. Methods: A. veronii CTe-01 was characterized using standard microbiological and molecular techniques. Antibiotic susceptibility and heavy metal resistance were tested per standard protocols. Genomic analysis, including plasmid characterization, was conducted in silico. Results: A. veronii CTe-01 showed resistance to various heavy metals and antibiotics. Multiple resistance genes were identified, including those for beta-lactamases, heavy metal resistance, and type III secretion system components. The bacterium carries a 9 kb plasmid with repA/repB replication genes, parA/parB partitioning genes, and a type II toxin-antitoxin system for stability. Conclusions: A. veronii CTe-01 is a genetic reservoir for antibiotic resistance, heavy metal resistance genes, and virulence factors. The study offers insights into its dual role as a pathogen and heavy metal remediator in aquatic environments.

引用

页数：7

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