Case report: A rare case of malignant solitary fibrous tumor in an adult with an epithelioid pattern in the occipital region

被引:0
作者
Huang, Ke [1 ]
Liu, Wen-wen [1 ]
Chen, Xiu-wen [1 ]
Hao, Yin-hua [1 ]
Luo, Sen-yuan [1 ]
Yuan, Ling-ling [1 ]
Huang, Yu-gang [1 ]
Tang, Xian-bin [1 ]
机构
[1] Hubei Univ Med, Taihe Hosp, Dept Pathol, Shiyan, Peoples R China
来源
FRONTIERS IN ONCOLOGY | 2024年 / 14卷
关键词
case report; malignant solitary fibrous tumor; NAB2-STAT6; fusion; diagnostic pathology; Next-generation sequencing-NGS; CLASSIFICATION; SARCOMA; FIBROSARCOMA;
D O I
10.3389/fonc.2024.1339582
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
We illustrated a rare case of malignant solitary fibrous tumor (MSFT) with epithelioid morphology in the occipital region of a 59-year-old female, in which a rare NAB2ex7-STAT6 exon15/16 double fusion subtype was detected by the Next-generation sequencing (NGS) and STAT6 immunohistochemistry (IHC) was diffusely and strongly positively expressed, without recurrence after 20 months of postoperative follow-up. The morphological and molecular genetic aspects and the differential diagnosis are described, and the relevant literature was assessed in order to broaden our understanding and diagnostic capability of this malignancy.
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页数:7
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