Impacts of subjective cognitive decline and mild cognitive impairment on the effectiveness of an exercise intervention among community-dwelling (Pre)frail older adults

被引:3
作者
Zhou, Wendie [1 ]
Qiao, Xiaoxia [2 ]
Liu, Tingting [1 ]
Wen, Linlu [1 ]
Gao, Hui [1 ]
Wang, Caixia [1 ]
Jin, Yaru [1 ]
Si, Huaxin [1 ]
Bian, Yanhui [1 ]
Liu, Qinqin [1 ]
Li, Yanyan [1 ]
Yu, Jiaqi [1 ]
Wang, Cuili [1 ]
机构
[1] Peking Univ, 38 Xueyuan Rd, Beijing 100191, Peoples R China
[2] Shanxi Med Univ, 56 Xinjian South Rd, Taiyuan 030001, Peoples R China
基金
中国国家自然科学基金; 中国国家社会科学基金;
关键词
Subjective cognitive decline; Mild cognitive impairment; Frailty; Exercise intervention; Stepped-wedge cluster randomized trial; ASIAN WORKING GROUP; PHYSICAL-EXERCISE; FRAILTY; CONSENSUS; ASSOCIATION; DISABILITY; SARCOPENIA; FRAMEWORK; VERSION; SCALE;
D O I
10.1016/j.jpsychires.2024.08.029
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Background: Subjective cognitive decline (SCD) is prevalent in community-dwelling (pre)frail older adults. This study aimed to investigate whether baseline subjective cognitive decline (SCD) and mild cognitive impairment (MCI) impacted the effectiveness of an exercise intervention among (pre)frail older adults. Methods: This is a post hoc analysis of a stepped-wedge cluster randomized trial among (pre)frail older adults across six communities. The intervention effectiveness was examined among (pre)frail older people among subgroups with normal cognition (n = 44), SCD (n = 58), or MCI (n = 30). Results: The normal cognition group had both immediate and persistent treatment responses to most outcomes. The SCD group showed positive responses to frailty (0-, 12-, 24 week), ambulation and dynamic balance (0week), and depressive symptoms (12-week). The MCI group exhibited immediate improvement in frailty, cognition, depressive symptoms, social support and QoL, which persisted only in frailty status, social support and mental QoL at follow-ups. The MCI group showed superior immediate responses to cognitive function and depressive symptoms compared to another two subgroups. No differences were found between the normal cognition and SCD groups except for cognitive status (12-week). Conclusions: (Pre)frail people with SCD or MCI had fewer improved outcomes compared to those with normal cognition regardless of immediate or persistent improvements. The incorporation of cognitive strategies with exercise interventions are recommended among (pre)frail older adults with SCD or MCI.
引用
收藏
页码:313 / 321
页数:9
相关论文
共 58 条
[1]   Physical Exercise as Therapy for Frailty [J].
Aguirre, Lina E. ;
Villareal, Dennis T. .
FRAILTY: PATHOPHYSIOLOGY, PHENOTYPE AND PATIENT CARE, 2015, 83 :83-92
[2]   Asian Working Group for Sarcopenia: 2019 Consensus Update on Sarcopenia Diagnosis and Treatment [J].
Chen, Liang-Kung ;
Woo, Jean ;
Assantachai, Prasert ;
Auyeung, Tung-Wai ;
Chou, Ming-Yueh ;
Iijima, Katsuya ;
Jang, Hak Chul ;
Kang, Lin ;
Kim, Miji ;
Kim, Sunyoung ;
Kojima, Taro ;
Kuzuya, Masafumi ;
Lee, Jenny S. W. ;
Lee, Sang Yoon ;
Lee, Wei-Ju ;
Lee, Yunhwan ;
Liang, Chih-Kuang ;
Lim, Jae-Young ;
Lim, Wee Shiong ;
Peng, Li-Ning ;
Sugimoto, Ken ;
Tanaka, Tomoki ;
Won, Chang Won ;
Yamada, Minoru ;
Zhang, Teimei ;
Akishita, Masahiro ;
Arai, Hidenori .
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION, 2020, 21 (03) :300-+
[3]   Sarcopenia in Asia: Consensus Report of the Asian Working Group for Sarcopenia [J].
Chen, Liang-Kung ;
Liu, Li-Kuo ;
Woo, Jean ;
Assantachai, Prasert ;
Auyeung, Tung-Wai ;
Bahyah, Kamaruzzaman Shahrul ;
Chou, Ming-Yueh ;
Chen, Liang-Yu ;
Hsu, Pi-Shan ;
Krairit, Orapitchaya ;
Lee, Jenny S. W. ;
Lee, Wei-Ju ;
Lee, Yunhwan ;
Liang, Chih-Kuang ;
Limpawattana, Panita ;
Lin, Chu-Sheng ;
Peng, Li-Ning ;
Satake, Shosuke ;
Suzuki, Takao ;
Won, Chang Won ;
Wu, Chih-Hsing ;
Wu, Si-Nan ;
Zhang, Teimei ;
Zeng, Ping ;
Akishita, Masahiro ;
Arai, Hidenori .
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION, 2014, 15 (02) :95-101
[4]   Understanding the Episodic Memory and Executive Functioning Axis Impairment in MCI Patients: A Multicenter Study in Comparison with CSF Biomarkers [J].
Chino, Brenda ;
Torres-Simon, Lucia ;
Zelwetro, Agnieszka ;
Concepcion Rodriguez-Rojo, Inmaculada ;
Carnes-Vendrell, Anna ;
Pinol-Ripoll, Gerard ;
Yubero, Raquel ;
Paul, Nuria ;
Maestu, Fernando .
BIOMEDICINES, 2023, 11 (12)
[5]  
Cohen J., 1988, Statistical Power Analysis for the Behavioral Sciences., V2nd, DOI [DOI 10.1007/978-1-4684-5439-0_2, DOI 10.4324/9780203771587, 10.4324/9780203771587]
[6]   The Tortoise Factor - Get FITT [J].
DeSimone, Grace T. .
ACSMS HEALTH & FITNESS JOURNAL, 2019, 23 (02) :3-4
[7]   Adherence to exercise interventions in older people with mild cognitive impairment and dementia: A systematic review and meta-analysis [J].
Di Lorito, Claudio ;
Bosco, Alessandro ;
Booth, Vicky ;
Goldberg, Sarah ;
Harwood, Rowan H. ;
Van der Wardt, Veronika .
PREVENTIVE MEDICINE REPORTS, 2020, 19
[8]   The relevance of nutrition for the concept of cognitive frailty [J].
Dominguez, Ligia J. ;
Barbagallo, Mario .
CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE, 2017, 20 (01) :61-68
[9]   Cross-Cultural Adaptation and Validation of the FRAIL Scale in Chinese Community-Dwelling Older Adults [J].
Dong, Lijuan ;
Qiao, Xiaoxia ;
Tian, Xiaoyu ;
Liu, Na ;
Jin, Yaru ;
Si, Huaxin ;
Wang, Cuili .
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION, 2018, 19 (01) :12-17
[10]   Frailty Is Related to Subjective Cognitive Decline in Older Women without Dementia [J].
Gifford, Katherine A. ;
Bell, Susan P. ;
Liu, Dandan ;
Neal, Jacquelyn E. ;
Turchan, Maxim ;
Shah, Avantika S. ;
Jefferson, Angela L. .
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 2019, 67 (09) :1803-1811