A highly specific red-emitting fluorescent probe for monitoring of Cu2+ in living cells and zebrafish

被引：0
|
作者：
Kong, Shuai [1 ]
Zhang, Yan [1 ]
Xie, Lianke [1 ]
Qi, Guodong [1 ]
Li, Yanping [2 ]
Dai, Haitao [3 ]
Qi, Qiubo [1 ]
Chen, Yimin [1 ]
机构：
[1] State Grid Shandong Elect Power Res Inst, Jinan 250003, Peoples R China
[2] State Grid Shandong Elect Power Co, Jinan, Peoples R China
[3] State Grid Shandong Elect Power Extrahigh Power Co, Jinan, Peoples R China
来源：
LUMINESCENCE | 2024年 / 39卷 / 09期
关键词：
bioimaging; Cu2+; fluorescent probe; seminaphthorhodafluor; SENSOR;
D O I：
10.1002/bio.4886
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
A novel seminaphthorhodafluor-based fluorescent probe was designed and prepared. It exhibited an outstanding off-on fluorescence response (about 45-fold enhancement) to Cu2+ because the structure changed from a spirocyclic form to a ring-open state. It showed satisfactory detection performances for Cu2+ with fast response speed, high selectivity and anti-interference, and a low detection limit (22.9 nM) due to its long emission wavelength and off-on fluorescence response mode. This probe was also satisfactorily applied for the monitoring of Cu2+ in living cells and zebrafish.
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页数：6
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