Omalizumab for management of hypersensitivity reactions to anticancer drugs

被引：1

作者：

Grover, Piyush ^{[1
,2
,3
]}

Krummenacher, Matthew ^{[1
]}

Loy, Timothy ^{[1
]}

Nowak, Anna K. ^{[2
]}

Lucas, Michaela ^{[1
,2
,4
,5
]}

机构：

[1] Sir Charles Gairdner Hosp, Dept Immunol, Perth, WA, Australia

[2] Univ Western Australia, Med Sch, Perth, WA, Australia

[3] Fiona Stanley Hosp, Dept Med Oncol, Perth, WA, Australia

[4] Perth Childrens Hosp, Dept Immunol, Perth, WA, Australia

[5] PathWest, Perth, WA, Australia

来源：

INTERNAL MEDICINE JOURNAL | 2024年 / 54卷 / 08期

关键词：

allergy; cancer drugs; omalizumab; desensitisation; DESENSITIZATION; IGE; ASTHMA;

D O I：

10.1111/imj.16464

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Hypersensitivity reactions to anticancer drugs include treatment-limiting toxicity. Standard drug desensitisation offers temporary tolerance and hence requires repetition. We used omalizumab, an anti-immunoglobulin E antibody, to overcome immediate and delayed hypersensitivity reactions to various anticancer drugs. Seven of the eight patients in the current study successfully resumed the desired anticancer drug regimen without standard desensitisation. No safety issues from omalizumab were observed.

引用

页码：1396 / 1400

页数：5

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