New horizons in geographic atrophy treatment: enthusiasm and caution surrounding complement inhibitors

被引:0
作者
Lai, Eric [1 ]
Lee, Timothy [2 ]
Lee, Claire [3 ]
Schechet, Sidney A. [3 ]
机构
[1] Yale Sch Med, Ophthalmol & Visual Sci, New Haven, CT USA
[2] Walter Reed Natl Mil Med Ctr, Ophthalmol, Bethesda, MD USA
[3] Elman Retina Grp, Baltimore, MD 21229 USA
来源
BMJ OPEN OPHTHALMOLOGY | 2024年 / 9卷 / 01期
关键词
Clinical Trial; Degeneration; Macula; Pharmacology; Retina; Treatment Medical; MACULAR DEGENERATION; PROGRESSION; SECONDARY; DISEASE;
D O I
10.1136/bmjophth-2024-001854
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
引用
收藏
页数:6
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共 25 条
  • [11] Progression of Geographic Atrophy in Age-related Macular Degeneration AREDS2 Report Number 16
    Keenan, Tiarnan D.
    Agron, Elvira
    Domalpally, Amitha
    Clemons, Traci E.
    van Asten, Freekje
    Wong, Wai T.
    Danis, Ronald G.
    Sadda, SriniVas
    Rosenfeld, Philip J.
    Klein, Michael L.
    Ratnapriya, Rinki
    Swaroop, Anand
    Ferris, Frederick L., III
    Chew, Emily Y.
    [J]. OPHTHALMOLOGY, 2018, 125 (12) : 1913 - 1928
  • [12] Efficacy and safety of avacincaptad pegol in patients with geographic atrophy (GATHER2): 12-month results from a randomised, double-masked, phase 3 trial
    Khanani, Arshad M.
    Patel, Sunil S.
    Staurenghi, Giovanni
    Tadayoni, Ramin
    Danzig, Carl J.
    Eichenbaum, David A.
    Hsu, Jason
    Wykoff, Charles C.
    Heier, Jeffrey S.
    Lally, David R.
    Mones, Jordi
    Nielsen, Jared S.
    Sheth, Veeral S.
    Kaiser, Peter K.
    Clark, Julie
    Zhu, Liansheng
    Patel, Hersh
    Tang, Justin
    Desai, Dhaval
    Jaffe, Glenn J.
    [J]. LANCET, 2023, 402 (10411) : 1449 - 1458
  • [13] Kwak N, 2000, INVEST OPHTH VIS SCI, V41, P3158
  • [14] Systemic Complement Activation Profiles in Nonexudative Age-Related Macular Degeneration: A Meta-Analysis
    Lin, Jonathan B.
    Serghiou, Stylianos
    Miller, Joan W.
    Vavvas, Demetrios G.
    [J]. JOURNAL OF CLINICAL MEDICINE, 2022, 11 (09)
  • [15] Lindblad AS, 2009, ARCH OPHTHALMOL-CHIC, V127, P1168, DOI 10.1001/archophthalmol.2009.198
  • [16] Deep Learning-Based Prediction of Individual Geographic Atrophy Progression from a Single Baseline OCT
    Mai, Julia
    Lachinov, Dmitrii
    Reiter, Gregor S.
    Riedl, Sophie
    Grechenig, Christoph
    Bogunovic, Hrvoje
    Schmidt-Erfurth, Ursula
    [J]. OPHTHALMOLOGY SCIENCE, 2024, 4 (04):
  • [17] Geographic atrophy: clinical impact and emerging treatments
    Patel, Hershel R.
    Eichenbaum, David
    [J]. OPHTHALMIC SURGERY LASERS & IMAGING RETINA, 2015, 46 (01) : 8 - 13
  • [18] Spaide Richard F, 2024, Ophthalmol Retina, V8, pe24, DOI 10.1016/j.oret.2024.04.006
  • [19] Health Span vs Lifespan in Geographic Atrophy
    Spaide, Richard F.
    Vavvas, Demetrios G.
    [J]. JAMA OPHTHALMOLOGY, 2024, 142 (06) : 558 - 559
  • [20] COMPLEMENT INHIBITION FOR GEOGRAPHIC ATROPHY Review of Salient Functional Outcomes and Perspective
    Spaide, Richard F.
    Vavvas, Demetrios G.
    [J]. RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES, 2023, 43 (07): : 1064 - 1069