A Comprehensive Geriatric Workup and Frailty Assessment in Older Patients with Severe Aortic Stenosis

被引：6

作者：

Brunetti, Enrico ^{[1
,2
]}

Luca, Fabiana ^{[3
]}

Presta, Roberto ^{[1
]}

Marchionni, Niccolo ^{[2
]}

Boccanelli, Alessandro ^{[4
]}

Ungar, Andrea ^{[2
]}

Rao, Carmelo ^{[3
]}

Ingianni, Nadia ^{[5
]}

Lettino, Maddalena ^{[6
]}

Del Sindaco, Donatella ^{[7
]}

Murrone, Adriano ^{[8
]}

Riccio, Carmine ^{[9
]}

Colivicchi, Furio ^{[10
]}

Grimaldi, Massimo ^{[11
]}

Gulizia, Michele ^{[12
]}

Oliva, Fabrizio ^{[13
]}

Bo, Mario ^{[1
]}

Parrini, Iris ^{[14
]}

机构：

[1] Univ Turin, Hosp Citta Salute & Sci Torino, Dept Med Sci, Geriatr Unit, I-10126 Turin, Italy

[2] Univ Florence, Dept Expt & Clin Med, Largo G Brambilla 3, I-50134 Florence, Italy

[3] Grande Osped Metropolitano Reggio, Cardiol Dept, I-89124 Reggio Di Calabria, Italy

[4] UniCamillus Univ, I-00131 Rome, Italy

[5] Cardiol ASP, I-91100 Trapani, Italy

[6] Fdn IRCCS San Gerardo dei Tintori, Dept Cardiac Thorac & Vasc Dis, I-20900 Monza, Italy

[7] UOC Santo Spirito Nuova Regina Margher ASL Rome 1, I-00153 Rome, Italy

[8] AUSL Umbria 1, Osped Citta Castello & Gubbio Gualdo Tadino, SC Cardiol UTIC, I-06127 Perugia, Italy

[9] AORN St Anna & San Sebastiano, Div Clin Cardiol, I-81100 Caserta, Italy

[10] San Filippo Neri Hosp, Clin & Rehabil Cardiol Unit, I-00135 Rome, Italy

[11] Miulli Hosp, Cardiol Dept, I-70021 Acquaviva delle Fonti, Bari, Italy

[12] Garibaldi Nesima Hosp, Cardiol Dept, I-95122 Catania, Italy

[13] ASST Niguarda Hosp, Cardiovasc Dept A De Gasperis, I-20162 Milan, Italy

[14] Mauriziano Hosp, Dept Cardiol, I-10128 Turin, Italy

来源：

JOURNAL OF CLINICAL MEDICINE | 2024年 / 13卷 / 14期

关键词：

transcatheter aortic valve implantation; elderly; side adverse; frailty; CHRONIC KIDNEY-DISEASE; VALVE-REPLACEMENT; MITRAL REGURGITATION; CLINICAL-OUTCOMES; AMERICAN-COLLEGE; DECISION-MAKING; EUROSCORE II; TRANSCATHETER; IMPLANTATION; IMPACT;

D O I：

10.3390/jcm13144169

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Aortic stenosis (AS) represents a notable paradigm for cardiovascular (CV) and geriatric disorders owing to comorbidity. Transcatheter aortic valve replacement (TAVR) was initially considered a therapeutic strategy in elderly individuals deemed unsuitable for or at high risk of surgical valve replacement. The progressive improvement in TAVR technology has led to the need to refine older patients' stratification, progressively incorporating the concept of frailty and other geriatric vulnerabilities. Recognizing the intricate nature of the aging process, reliance exclusively on chronological age for stratification resulted in an initial but inadequate tool to assess both CV and non-CV risks effectively. A comprehensive geriatric evaluation should be performed before TAVR procedures, taking into account both physical and cognitive capabilities and post-procedural outcomes through a multidisciplinary framework. This review adopts a multidisciplinary perspective to delve into the diagnosis and holistic management of AS in elderly populations in order to facilitate decision-making, thereby optimizing outcomes centered around patient well-being.

引用

页数：20

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