The Effects of Exercise on Symptoms of Chemotherapy-Induced Peripheral Neuropathy in Cancer Survivors: A Systematic Review and Meta-Analysis

被引:2
作者
Khemthong, Usa [1 ]
Hawsawi, Samah [2 ]
Schneider, Joanne Kraenzle [2 ]
机构
[1] Chulabhorn Royal Acad, HRH Princess Chulabhorn Coll Med Sci, Fac Nursing, Bangkok, Thailand
[2] St Louis Univ, Trudy Busch Valentine Sch Nursing, St Louis, MO USA
关键词
chemotherapy-induced peripheral neuropathy; cancer survivors; exercise; PHYSICAL-ACTIVITY; STRENGTH;
D O I
10.1188/24.ONF.426-444
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
PROBLEM IDENTIFICATION: Chemotherapy-induced peripheral neuropathy (CIPN) can cause treatment delays or discontinuation. Exercise can improve CIPN, but the effects have been inconsistent. LITERATURE SEARCH: 12 databases and 5 websites were searched from database inception to December 22, 2023, for primary studies that were reported in English and examined the effects of exercise on CIPN in cancer survivors. DATA EVALUATION: 20 studies (N = 1,308 total participants) were identified and reviewed. SYNTHESIS: Using a random-effects model, exercise slightly improved symptoms of CIPN (Hedges’s g = 0.28, Hartung-Knapp adjusted 95% confidence interval [0.12, 0.45], p = 0.002). The 95% prediction interval showed that the true effect size of future studies would likely range from –0.1 to 0.66. Frequency of performing exercise moderated the effect size, further improving symptoms. IMPLICATIONS FOR NURSING: Nurses can encourage cancer survivors to engage in exercise, such as resistance training, aerobic exercise, balance training, and/or yoga. Nurses can refer cancer survivors to trained exercise specialists or provide information about finding a community exercise program for patients with cancer. © 2024, Oncology Nursing Society. All rights reserved.
引用
收藏
页码:426 / 444
页数:19
相关论文
共 45 条
[1]  
American Cancer Society, 2024, Peripheral neuropathy
[2]   Chemotherapy-induced peripheral neuropathy in adults: a comprehensive update of the literature [J].
Argyriou, Andreas A. ;
Kyritsis, Athanasios P. ;
Makatsoris, Thomas ;
Kalofonos, Haralabos P. .
CANCER MANAGEMENT AND RESEARCH, 2014, 6 :135-147
[3]   The Effect of Therapeutic Exercises on Balance, Quality of Life, and Pain in Patients Who Were Receiving Neurotoxic Chemotherapy [J].
Bahar-Ozdemir, Yeliz ;
Akyuz, Gulseren ;
Kalkandelen, Melihat ;
Yumuk, Perran Fulden .
AMERICAN JOURNAL OF PHYSICAL MEDICINE & REHABILITATION, 2020, 99 (04) :291-299
[4]   Yoga for Chemotherapy-Induced Peripheral Neuropathy and Fall Risk: A Randomized Controlled Trial [J].
Bao, Ting ;
Zhi, Iris ;
Baser, Raymond ;
Hooper, Madeline ;
Chen, Connie ;
Piulson, Lauren ;
Li, Qing S. ;
Galantino, Mary Lou ;
Blinder, Victoria ;
Robson, Mark ;
Seidman, Andrew ;
Panageas, Katherine S. ;
Mao, Jun J. .
JNCI CANCER SPECTRUM, 2020, 4 (06)
[5]   Effect of Exercise on Taxane Chemotherapy-Induced Peripheral Neuropathy in Women With Breast Cancer: A Randomized Controlled Trial [J].
Bland, Kelcey A. ;
Kirkham, Amy A. ;
Bovard, Joshua ;
Shenkier, Tamara ;
Zucker, David ;
McKenzie, Donald C. ;
Davis, Margot K. ;
Gelmon, Karen A. ;
Campbell, Kristin L. .
CLINICAL BREAST CANCER, 2019, 19 (06) :411-422
[6]  
Borenstein M., 2009, INTRO METAANALYSIS, DOI [10.1002/9780470743386, DOI 10.1002/9780470743386]
[7]   Effect of exercise before and/or during taxane-containing chemotherapy treatment on chemotherapy-induced peripheral neuropathy symptoms in women with breast cancer: systematic review and meta-analysis [J].
Brownson-Smith, Rosiered ;
Orange, Samuel T. ;
Cresti, Nicola ;
Hunt, Katherine ;
Saxton, John ;
Temesi, John .
JOURNAL OF CANCER SURVIVORSHIP, 2025, 19 (01) :78-96
[8]   Chemotherapy-Induced Peripheral Neuropathy: Epidemiology, Pathomechanisms and Treatment [J].
Burgess, Jamie ;
Ferdousi, Maryam ;
Gosal, David ;
Boon, Cheng ;
Matsumoto, Kohei ;
Marshall, Anne ;
Mak, Tony ;
Marshall, Andrew ;
Frank, Bernhard ;
Malik, Rayaz A. ;
Alam, Uazman .
ONCOLOGY AND THERAPY, 2021, 9 (02) :385-450
[9]   Effect of Exercise on Chemotherapy-Induced Peripheral Neuropathy Among Patients Treated for Ovarian Cancer A Secondary Analysis of a Randomized Clinical Trial [J].
Cao, Anlan ;
Cartmel, Brenda ;
Li, Fang-Yong ;
Gottlieb, Linda T. ;
Harrigan, Maura ;
Ligibel, Jennifer A. ;
Gogoi, Radhika ;
Schwartz, Peter E. ;
Esserman, Denise A. ;
Irwin, Melinda L. ;
Ferrucci, Leah M. .
JAMA NETWORK OPEN, 2023, 6 (08)
[10]   Chemotherapy-induced peripheral neuropathy: What do we know about mechanisms? [J].
Carozzi, V. A. ;
Canta, A. ;
Chiorazzi, A. .
NEUROSCIENCE LETTERS, 2015, 596 :90-107